Page last updated: 2024-11-07

ribonolactone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ribonolactone: structure given in first source; RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

D-ribono-1,4-lactone : A five-membered form of ribonolactone having D-configuration. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID111064
CHEMBL ID607627
CHEBI ID74168
SCHEMBL ID625893
MeSH IDM0159730

Synonyms (68)

Synonym
AC-15682
ribonic acid, gamma-lactone
3327-63-7
d-ribopentono-1,4-lactone
d-ribonolactone
5336-08-3
d-ribono-1,4-lactone
d-(+)-ribonic gamma-lactone, 97%
ribonolactone
93B77B8F-39C4-4159-83A4-A05A3F85E8C5
ribonic acid-1,4-lactone
d-(+)-ribonic acid gamma-lactone
d-(+)-ribono-1,4-lactone
d-(+)-ribonolactone
cuokhacjlgprhd-bxxzvtaosa-
inchi=1/c5h8o5/c6-1-2-3(7)4(8)5(9)10-2/h2-4,6-8h,1h2/t2-,3-,4-/m1/s1
chebi:74168 ,
CHEMBL607627
(3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-one
ribono-gamma-lactone
d-ribonic acid-1,4-lactone
d-ribono-1,4-lactone(d-(+)-ribonic acid gamma-lactone)
AKOS015955664
d-ribono-gamma-lactone
d-ribonolactone (van)
ribonic acid, gamma-lactone, d-
einecs 226-256-5
64e63nc231 ,
unii-64e63nc231
gamma-lactone of ribonic acid
(3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3h)-one
d-ribopentono-1,4-lacton
(+)-ribonolactone
d-(+)-ribonic acid lactone
ribonolactone [inci]
CS-M1132
SCHEMBL625893
mfcd00063241
d(+)-ribonic acid gamma-lactone
d-(+)-ribonic-g-lactone
W-201380
W-200055
J-517584
d-(+)-ribonic acid-gamma-lactone, puriss., >=99.0% (t)
delta-(+)-ribonone-1.4-lactone
delta-(+)-ribonic acid gamma-lactone
d-(+)-ribonic acid g-lactone
gamma-lactone-ribonic acid
delta-ribonolactone
delta-ribono-gamma-lactone
delta-ribopentono-1,4-lactone
d-(+)-ribonone-1.4-lactone
delta-(+)-ribonic acid g-lactone
gamma-lactone of ribonate
gamma-lactone-ribonate
E10111
A851419
d-ribonic acid g-lactone
CUOKHACJLGPRHD-BXXZVTAOSA-N
Q27144478
AS-46673
HY-76691
delta-ribono-1,4-lactone
AMY24722
(3s,4r,5s)-3,4-dihydroxy-5-(hydroxymethyl)-dihydrofuran-2(3h)-one;d-ribono-1,4-lactone
DTXSID201347750
(3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-one
rel-(3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3h)-one
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
ribonolactone
butan-4-olideAny gamma-lactone having the lactone moiety derived from 4-hydroxybutanoic acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID38908Inhibitory activity against Arabinose-5-phosphate isomerase at a concentration of 6 mM; Not active.1984Journal of medicinal chemistry, Jun, Volume: 27, Issue:6
Inhibition of arabinose 5-phosphate isomerase. An approach to the inhibition of bacterial lipopolysaccharide biosynthesis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (15.38)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.71

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.71 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index22.84 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.71)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]