| Assay ID | Title | Year | Journal | Article |
|---|
| AID1379136 | Inhibition of human Kv1.2 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1680917 | Neuroprotective activity against TBHP-induced human SH-SY5Y cells assessed as decrease in ROS production at 1 uM after 6 hrs by DCFH-DA dye based spectrophotometric assay relative to control | 2020 | Journal of natural products, 07-24, Volume: 83, Issue:7
| Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge |
| AID1379145 | Inhibition of rat Kv1.2 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379146 | Inhibition of rat Kv1.3 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379144 | Inhibition of rat Kv1.1 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379140 | Inhibition of human Kv1.6 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379137 | Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379150 | Inhibition of rat Kv10.1 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1680922 | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability at 0.001 to 10 uM after 24 hrs by MTT assay | 2020 | Journal of natural products, 07-24, Volume: 83, Issue:7
| Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge |
| AID1387660 | Inhibition of yeast chymotrypsin-like 20S proteasome using suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate addition measured every 2 mins for 1 hr by fluorescence assay | 2018 | Journal of natural products, 10-26, Volume: 81, Issue:10
| Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth. |
| AID1379135 | Inhibition of human Kv1.1 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379149 | Inhibition of rat Kv1.6 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1680920 | Neuroprotective activity against TBHP-induced cytotoxicity in human SH-SY5Y cells assessed as increase in cell viability at 0.001 uM after 6 hrs by MTT assay | 2020 | Journal of natural products, 07-24, Volume: 83, Issue:7
| Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge |
| AID1379138 | Inhibition of human Kv1.4 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1379139 | Inhibition of human Kv1.5 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp method | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1680916 | Inhibition of LPS-induced NO production in mouse BV-2 cells at 0.1 to 1 uM preincubated for 1 hrs followed by LPS-stimulation and measured after 24 hrs by Griess reagent based spectrophotometric assay | 2020 | Journal of natural products, 07-24, Volume: 83, Issue:7
| Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge |
| AID1379148 | Inhibition of rat Kv1.5 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| AID1680921 | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability at 0.001 to 10 uM after 24 hrs by MTT assay | 2020 | Journal of natural products, 07-24, Volume: 83, Issue:7
| Futunamine, a Pyrrole-Imidazole Alkaloid from the Sponge |
| AID1379147 | Inhibition of rat Kv1.4 expressed in Xenopus laevis oocytes at 1 uM at -90 mV holding potential by two-electrode voltage clamp assay relative to control | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | Clathrodin, hymenidin and oroidin, and their synthetic analogues as inhibitors of the voltage-gated potassium channels. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |