esterastin profile

esterastin: inhibitor of esterases; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	22256690
MeSH ID	M0067964

Synonym
esterastin
67655-93-0

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	9 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	3 (30.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (70.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
glycine [no description available]	4.49	4	alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid	EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.37	2	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
leucine Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.	4.26	3	amino acid zwitterion; L-alpha-amino acid; leucine; proteinogenic amino acid; pyruvate family amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
ethyl butyrate ethyl butyrate : A butyrate ester resulting from the formal condensation of the hydroxy group of ethanol with the carboxy group of butyric acid.	1.96	1	butyrate ester	plant metabolite
paraoxon [no description available]	1.96	1	aryl dialkyl phosphate; organophosphate insecticide	EC 3.1.1.7 (acetylcholinesterase) inhibitor; mouse metabolite
forphenicine forphenicine: alkaline phosphatase inhibitor from Actinomycetes; structure	4.49	4
forphenicinol [no description available]	3.06	1
ubenimex ubenimex: growth inhibitor	4.26	3
fk 156 FK 156: structure given in first source; RN given refers to ((L)(R)-isomer	3.06	1
coriolin coriolin: sesquiterpene antibiotic isolated from Coriolus consors; structure in third source	3.46	2
arphamenine b arphamenine B: from Chromobacterium violaceum; structure given in second source	3.47	2
diaminopimelic acid Diaminopimelic Acid: A diamino derivative of heptanedioic acid with amino groups at C-2 and C-6 and the general formula (COOH)CH(NH2)CH2CH2CH2CH(NH2)(COOH).. LL-2,6-diaminopimelic acid : A 2,6-diaminopimelic acid in which both chiral centres have S configuration. It is a component of bacterial cell wall.	3.06	1	2,6-diaminopimelic acid; amino acid zwitterion	Escherichia coli metabolite
amastatin amastatin: structure; inhibits aminopeptidase. amastatin : A tetrapeptide comprising (2S,3R)-3-amino-2-hydroxy-5-methylhexanoyl, L-valyl, L-valyl and L-aspartic acid units joined in sequence	4.26	3	tetrapeptide	EC 3.4.11.* (aminopeptidase) inhibitor; protease inhibitor
sesquiterpenes [no description available]	3.46	2
1-monooleoyl-rac-glycerol Peceol: lipid excipient containing readily dispersible mixture of mono- & diglycerides of oleic acid. 1-oleoylglycerol : A 1-monoglyceride where the acyl group is oleoyl.. monooleoylglycerol : A monoglyceride in which the acyl group is oleoyl with the position of acylation unspecified.	1.96	1	1-acylglycerol 18:1; monooleoylglycerol	plant metabolite
cholesteryl oleate cholesteryl oleate: RN given refers to ((Z)-isomer). cholesteryl oleate : The (Z)-stereoisomer of cholesteryl octadec-9-enoate.	1.96	1	CE(18:1); cholesteryl octadec-9-enoate	mouse metabolite
ebelactone a ebelactone A: esterase inhibitor; structure given in first source	3.98	2
ebelactone b ebelactone B: esterase inhibitor; structure given in first source; see also ebelactone A	3.06	1
cholesteryl oleyl ether cholesteryl oleyl ether: not as rapidly degraded as the cholesterol esters; RN given refers to (3beta(Z))-isomer	6.97	1
arphamenine a arphamenine A: from Chromobacterium violaceum; structure given in second source	3.98	2

Condition	Relationship Strength	Studies
Allergic Encephalomyelitis [description not available]	1.96	1
Delayed Hypersensitivity [description not available]	3.28	2
Experimental Neoplasms [description not available]	3.28	2
Leukemia L 1210 [description not available]	2.88	1
Infection [description not available]	2.88	1
Infections Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.	2.88	1
Arteriosclerosis Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.	1.96	1

esterastin

Description

Cross-References

Synonyms (2)

Research

Studies (9)

Study Types

esterastin

Description

Cross-References

Synonyms (2)

Research

Studies (9)

Study Types

Related Drugs (20)

Related Conditions (7)