| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
carbonic acid
Carbonic Acid: Carbonic acid (H2C03). The hypothetical acid of carbon dioxide and water. It exists only in the form of its salts (carbonates), acid salts (hydrogen carbonates), amines (carbamic acid), and acid chlorides (carbonyl chloride). (From Grant & Hackh's Chemical Dictionary, 5th ed) | 2.1 | 1 | 0 | carbon oxoacid;
chalcocarbonic acid | mouse metabolite |
urethane
[no description available] | 2.1 | 1 | 0 | carbamate ester | fungal metabolite;
mutagen |
vinyl carbamate
vinyl carbamate: promutagen & more carcinogenic analog of ethyl carbamate (urethane); structure | 7.1 | 1 | 0 | carbamate ester | |
myxovirescin a
myxovirescin A: from Myxococcus virescens; structure given in first source | 2.06 | 1 | 0 | | |
fidaxomicin
Fidaxomicin: A narrow-spectrum macrolide antibacterial agent that is used in the treatment of diarrhea associated with CLOSTRIDIUM DIFFICILE INFECTION.. fidaxomicin : An 18-membered macrolide that is a fermentation product obtained from the Actinomycete Dactylosporangium aurantiacum. A narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections. | 3.57 | 2 | 0 | | |
ripostatin b
ripostatin B: an inhibitor of eubacterial RNA polymerase; isolated from Sorangium cellulosum; a macrocyclic lactone carbonic acid; structure given in first source | 3.16 | 1 | 0 | | |
ripostatin a
ripostatin A: an inhibitor of eubacterial RNA polymerase; a macrocyclic lactone carbonic acid; isolated from Sorangium cellulosum; structure given in first source | 3.55 | 2 | 0 | | |
rifampin
Rifampin: A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160) | 2.78 | 3 | 0 | cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion | angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor |
prodigiosin
Prodigiosin: 4-Methoxy-5-((5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl)- 2,2'-bi-1H-pyrrole. A toxic, bright red tripyrrole pigment from Serratia marcescens and others. It has antibacterial, anticoccidial, antimalarial, and antifungal activities, but is used mainly as a biochemical tool.. prodigiosin : A member of the class of tripyrroles that is a red-coloured pigment with antibiotic properties produced by Serratia marcescens. | 7.1 | 1 | 0 | | |
myxopyronin a
myxopyronin A: from Myxococcus fulvus; structure given in first source | 4.09 | 4 | 0 | | |
undecylprodigiosin
prodigiosin 25C: red pigment produced by Streptomyces hiroshimensis; potent immunosuppressive agent with its primary effect on functions of T cells; structure given in first source. undecylprodigiosin : A member of the class of tripyrroles that is 1H-pyrrole substituted by (4'-methoxy-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl and undecyl groups at positions 2 and 5, respectively. It is a pigment produced by Stveptomyces coelicolor. | 7.1 | 1 | 0 | alkaloid;
aromatic ether;
tripyrrole | antibacterial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite;
biological pigment;
immunosuppressive agent;
radiosensitizing agent |