Compounds > 3-chlorolactate
Page last updated: 2024-12-07

3-chlorolactate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-Chlorolactate, also known as 2-hydroxy-3-chloropropanoate, is a synthetic compound with potential applications in various fields. It is a chiral molecule, with two enantiomers: (R)-3-chlorolactate and (S)-3-chlorolactate. The compound has been studied for its potential as a precursor for the synthesis of other valuable chemicals, including pharmaceuticals. It has been investigated for its inhibitory effects on certain enzymes, particularly those involved in carbohydrate metabolism, making it a subject of interest for research in metabolic disorders. 3-Chlorolactate has also been explored for its potential use in polymer chemistry. The study of this compound is driven by its potential applications in various fields and the desire to understand its biological effects.'

3-chlorolactate: RN given refers to parent cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

3-chlorolactic acid : A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is replaced by a chloro group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID92899
CHEBI ID77855
SCHEMBL ID574040
MeSH IDM0049890

Synonyms (41)

Synonym
beta-chlorolactic acid, >=92.5%
3-chlorolactate
50906-02-0
AKOS003349157
3-chloro-2-hydroxypropanoic acid
FT-0690330
unii-m4y6ua6h9u
3-chlorolactic acid
3-chloro-2-hydroxypropionic acid
m4y6ua6h9u ,
propanoic acid, 3-chloro-2-hydroxy-
einecs 216-993-0
beta-chlorolactic acid
1713-85-5
2-hydroxy-3-chloropropionic acid
dl-3-chlorolactic acid
|a-chlorolactic acid
FT-0633790
AKOS017259380
SCHEMBL574040
CHEBI:77855
propanoic acid, chloro-2-hydroxy-
3-chloro-2-hydroxypropanoic acid #
3-chloro-2-hydroxypropanoicacid
74792-92-0
.beta.-chlorolactic acid
(+/-)-3-chlorolactic acid
dl-.beta.-chlorolactic acid
3-chlorolactic acid, (+/-)-
FT-0699410
mfcd00046523
J-010721
-chlorolactic acid
Q27147463
AS-42289
DTXSID10883745
beta-chlorolacticacid
EN300-85786
CS-0186802
3-chloro-2-hydroxy propanoic acid
beta -chlorolactic acid

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" While some degrees of inhibition of metabolic activity were evident, these compounds were not responsible for the toxic effects produced by (R)-3-chlorolactate."( The renal toxicity of (R)-3-chlorolactate in the rat.
Jones, AR; Porter, KE, 1987)		0.77
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
2-hydroxy monocarboxylic acid
organochlorine compoundAn organochlorine compound is a compound containing at least one carbon-chlorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (62.50)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's2 (25.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.83

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.83 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.83)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (12.50%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (87.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetone
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).		1.9710ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.		3.8121alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
alpha-chlorohydrin
alpha-Chlorohydrin: A chlorinated PROPANEDIOL with antifertility activity in males used as a chemosterilant in rodents.. 3-chloropropane-1,2-diol : A chloropropane-1,2-diol that is propane-1,2-diol substituted by a chloro group at position 3.		4.3241chloropropane-1,2-diol
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		1.9510dihydrogen
chlorine
Chlorine: An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.		1.9510diatomic chlorine;
gas molecular entity		bleaching agent
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		1.9510benzenes;
phenyl acetates
cl 88236
CL 88236: RN given refers to parent cpd without isomeric designation; structure		2.3720
acetyl coenzyme a
Acetyl Coenzyme A: Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.		1.9710acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
D-fructopyranose
[no description available]		1.9710cyclic hemiketal;
D-fructose;
fructopyranose		sweetening agent
concanavalin a
Concanavalin A: A MANNOSE/GLUCOSE binding lectin isolated from the jack bean (Canavalia ensiformis). It is a potent mitogen used to stimulate cell proliferation in lymphocytes, primarily T-lymphocyte, cultures.		2.0210
ConditionIndicatedRelationship StrengthStudiesTrials
Glycosuria
The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).		02.3720