Page last updated: 2024-12-07

2,2'-biimidazole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2'-Biimidazole is a heterocyclic compound with two imidazole rings connected at the 2 and 2' positions. It is a versatile building block for the synthesis of various heterocyclic compounds with potential applications in diverse fields. Synthesis of 2,2'-biimidazole typically involves condensation reactions of imidazole derivatives. Research on 2,2'-biimidazole has focused on its applications in coordination chemistry, as it forms stable complexes with metal ions. These complexes exhibit interesting properties, including luminescence and catalytic activity. Additionally, 2,2'-biimidazole derivatives have shown potential in medicinal chemistry as antimicrobial agents, anticancer drugs, and inhibitors of enzymes. The study of 2,2'-biimidazole is driven by its unique structure and its ability to coordinate with metal ions, leading to a wide range of potential applications in different fields.'

2,2'-biimidazole: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID101463
CHEMBL ID333830
SCHEMBL ID81650
MeSH IDM0180204

Synonyms (32)

Synonym
nsc522950
492-98-8
2,2'-biimidazole
nsc-522950
1h,1'h-[2,2']biimidazolyl
CHEMBL333830
2-(1h-imidazol-2-yl)-1h-imidazole
AKOS005609260
STK792841
1h,1'h-2,2'-biimidazole
wez56mm6ec ,
unii-wez56mm6ec
nsc 522950
h2biim
einecs 207-768-8
2,2'-bi-1h-imidazole
FT-0676583
1'h-2,2'-biimidazole
AZUHIVLOSAPWDM-UHFFFAOYSA-N
2,2'bi-1h-imidazole
SCHEMBL81650
bisimidazole
B2487 ,
mfcd00047014
DTXSID30197715
CS-W021324
DS-4584
SY041535
2,2 inverted exclamation mark -biimidazole
YSWG105
n-(2,6-diethylphenylcarbamoylmethyl)iminodiaceticanhydride
A871823
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID17398525% increase in left ventricular contractility (dP/dtmax) on iv administration in anesthetized rat1990Journal of medicinal chemistry, Jan, Volume: 33, Issue:1
Synthesis and cardiotonic activity of novel biimidazoles.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's4 (33.33)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.47

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.47 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.47)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]