bradykinin, hydroxy-Pro(3)-: in methanol extracts of skin from frog Heleophryne; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
[Hyp(3)]-bradykinin : An oligopeptide that is an analogue of bradykinin in which the third amino acid, proline, is replaced with hydroxyproline. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 169947 |
| CHEBI ID | 133051 |
| MeSH ID | M0076952 |
| Synonym |
|---|
| [hyp3]-bradykinin |
| l-arg-l-pro-l-hyp-gly-l-phe-l-ser-l-pro-l-phe-l-arg |
| bradykinin hydroxyproline |
| bradykinin hydroxy-pro(3) |
| 3-(l-4-hydroxyproline)bradykinin |
| arg-pro-hyp-gly-phe-ser-pro-phe-arg |
| 3-hydroxy-pro-bradykinin |
| 37642-65-2 |
| l-arginyl-l-prolyl-(4r)-4-hydroxy-l-prolylglycyl-l-phenylalanyl-l-seryl-l-prolyl-l-phenylalanyl-l-arginine |
| [hyp(3)]-bradykinin |
| arg-3-hyp-bradykinin |
| hydroxy-pro(3)-bradykinin |
| hydroxyproline(3)-bradykinin |
| CHEBI:133051 |
| bradykinin, arg-hyp(3)- |
| (2s)-2-[[(2s)-2-[[(2s)-1-[(2s)-2-[[(2s)-2-[[2-[[(2s,4r)-1-[(2s)-1-[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carb |
| bradykinin, hydroxyproline(3)- |
| bradykinin, hydroxy-pro(3)- |
| AKOS015903400 |
| JXRLHZCEMXTCBN-DIBGMJQNSA-N |
| (2s)-2-[(2s)-2-{[(2s)-1-[(2s)-2-[(2s)-2-(2-{[(2s,4r)-1-{[(2s)-1-[(2s)-2-amino-5-[(diaminomethylidene)amino]pentanoyl]pyrrolidin-2-yl]carbonyl}-4-hydroxypyrrolidin-2-yl]formamido}acetamido)-3-phenylpropanamido]-3-hydroxypropanoyl]pyrrolidin-2-yl]formamido} |
| [hyp3]-bradykinin, >=97% (hplc) |
| arg-hyp(3)-bradykinin |
| HY-P3061 |
| CS-0144127 |
| Role | Description |
|---|---|
| human urinary metabolite | Any metabolite (endogenous or exogenous) found in human urine samples. |
| bradykinin receptor agonist | An agonist that binds to and activates bradykinin receptors |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| oligopeptide | A peptide containing a relatively small number of amino acids. |
| peptide hormone | Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.11) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||