Page last updated: 2024-12-08

1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane is a synthetic compound that is not commonly known or studied.

There are a couple of reasons why this could be the case:

1. **Unusual/Incorrect Name:** The name itself might be incorrectly formatted or represent a compound that doesn't exist or has a different, more standard name. It's possible that the name was created for a specific research project and isn't part of the general chemical nomenclature.
2. **Lack of Research:** The compound could be a newly synthesized molecule or a derivative of an existing one that hasn't been extensively studied yet. There might not be enough research done to establish its significance or importance.

**To help you find more information, I need some context:**

* **Where did you encounter this name?** Was it in a scientific paper, a textbook, or another source?
* **What is the research context?** What field of study is this compound related to (e.g., pharmaceuticals, materials science, environmental chemistry)?

With more information, I can try to identify the compound and explain its potential relevance.

Cross-References

ID SourceID
PubMed CID183679
CHEBI ID34026
SCHEMBL ID15263150
MeSH IDM0479996

Synonyms (21)

Synonym
unii-y8i9cwq645
monodemethylmethoxychlor
phenol, 4-(2,2,2-trichloro-1-(4-methoxyphenyl)ethyl)-
4-(2,2,2-trichloro-1-(4-methoxyphenyl)ethyl)phenol
y8i9cwq645 ,
monohydroxymethoxychlor
1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane
28463-03-8
4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]phenol
mono-hydroxy methoxychlor
124042-16-6
phenol, 4-(2,2,2-trichloro-1-(4-methoxyphenyl)ethyl)-, labeled with carbon-14
2-(4-methoxyphenyl)-2-(4-hydroxyphenyl)-1,1,1-trichloroethane
2-(p-hydroxyphenyl)-2-(p-methoxyphenyl)-1,1,1-trichloroethane
phenol, p-(p-methoxy-.alpha.-(trichloromethyl)benzyl)-
demethyl methoxychlor
CHEBI:34026
SCHEMBL15263150
DTXSID0022482
Q27115759
phenol, 4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]-

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Cytochrome P450 enzymes metabolize MXC to mono-OH MXC (1,1,1-trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane [mono-OH]) and bis-OH MXC (1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane [HPTE]), two compounds that are proposed to be more toxic than the parent compound, can interact with the estrogen receptor (ER), and are proposed to be responsible for ovarian toxicity."( Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways.
Flaws, JA; Gupta, RK; Miller, KP, 2006
)
0.58
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
diarylmethaneAny compound containing two aryl groups connected by a single C atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.64

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.64 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.59 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.64)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]