Compounds > malyngolide

Page last updated: 2024-12-08

malyngolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

malyngolide: from blue-green algea, Lyngbya majuscula; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	155655
CHEMBL ID	475070
CHEBI ID	189316
SCHEMBL ID	10802270
MeSH ID	M0180057

Synonyms (10)

Synonym
malyngolide
(-)-malyngolide
CHEMBL475070
71582-80-4
CHEBI:189316
(3r,6s)-6-(hydroxymethyl)-3-methyl-6-nonyloxan-2-one
2h-pyran-2-one, tetrahydro-6-(hydroxymethyl)-3-methyl-6-nonyl-, (3r-trans)-
DTXSID80221812
malingolide
SCHEMBL10802270

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
aliphatic alcohol	An alcohol derived from an aliphatic compound.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (6)

Assay ID	Title	Year	Journal	Article
AID376022	Antibacterial activity against Bacillus subtilis ATCC 6051 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376019	Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376023	Antibacterial activity against Staphylococcus aureus ATCC 12600 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376018	Antifungal activity against Candida albicans ATCC 14053 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376020	Antibacterial activity against Escherichia coli ATCC 11775 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
AID376021	Antibacterial activity against Salmonella choleraesuis subsp. choleraesuis ATCC 14028 at 100 ug/disk by paper disk agar plate method	1999	Journal of natural products, Sep, Volume: 62, Issue:9	Tanikolide, a toxic and antifungal lactone from the marine cyanobacterium Lyngbya majuscula.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	2 (28.57)	29.6817
2010's	3 (42.86)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
chloroquine Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.	2.05	1	0	aminoquinoline; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antimalarial; antirheumatic drug; autophagy inhibitor; dermatologic drug
tanikolide tanikolide: structure in first source	2.42	2	0
aluminum Aluminum: A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98.	2	1	0	boron group element atom; elemental aluminium; metal atom
dragonamide c dragonamide C: from marine cyanobacterium Lyngbya majuscula; structure in first source	2.1	1	0

Condition	Indicated	Relationship Strength	Studies	Trials
Candida Infection [description not available]	0	2.1	1	0
Cronobacter Infections [description not available]	0	2.1	1	0
Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)	0	2.1	1	0
Enterobacteriaceae Infections Infections with bacteria of the family ENTEROBACTERIACEAE.	0	2.1	1	0