| Assay ID | Title | Year | Journal | Article |
|---|
| AID55051 | Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs after intravenous administration at a dose of 10 mg/kg | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists. |
| AID55230 | Dissociation constant towards Cysteinyl leukotriene D4 receptor of guinea pig | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists. |
| AID78376 | Antagonistic effect on LTD4 induced change in lung compliance (CDYN) in anesthetized guinea pig, at dose 5 ug/kg, administered intravenously | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists. |
| AID55049 | Inhibition of leukotriene D4 induced bronchoconstriction in anesthetized guinea pigs after aerosol administration as 1% solution | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists. |
| AID55229 | Binding constant was determined as affinity to displace [3H]LTD4 from Cysteinyl leukotriene D4 receptor on guinea pig lung membrane | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists. |
| AID55064 | Compound is evaluated for its ability to inhibit [3H]LTD4 binding to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes | 1986 | Journal of medicinal chemistry, Aug, Volume: 29, Issue:8
| Synthesis and structure-activity relationship studies of a series of 5-aryl-4,6-dithianonanedioic acids and related compounds: a novel class of leukotriene antagonists. |
| AID73699 | In vitro ability to antagonize a leukotriene D4 induced contraction of guinea pig trachea. | 1986 | Journal of medicinal chemistry, Aug, Volume: 29, Issue:8
| Synthesis and structure-activity relationship studies of a series of 5-aryl-4,6-dithianonanedioic acids and related compounds: a novel class of leukotriene antagonists. |
| AID55057 | Inhibitory activity of compound to block binding of radiolabeled Cysteinyl leukotriene D4 receptor sites in homogenized guinea pig lung at 10 uM | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| 3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists. |
| AID78375 | Antagonistic effect on LTD4 induced change in air way resistance (RL) in anesthetized guinea pigs, at dose 5 ug/kg, administered intravenously | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Synthesis and pharmacological characterization of 5-(2-dodecylphenyl)-4,6-dithianonanedioic acid and 5-[2-(8-phenyloctyl)phenyl]-4,6-dithianonanedioic acid: prototypes of a novel class of leukotriene antagonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |