Page last updated: 2024-12-07
r 84760
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
R 84760: kappa opioid receptor agonist; R-84760 is the (1R,2S)-isomer; R-86428 is the (1S,2R)-isomer; R-84761 is the (1R,2R)-isomer; R-86436 is the (1S,2S)-isomer; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 133035 |
MeSH ID | M0240662 |
Synonyms (22)
Synonym |
---|
gw7gy73veg , |
unii-gw7gy73veg |
157824-23-2 |
r 84760 |
r 86436 |
r 84761 |
r-84760 |
3-(1-pyrrolidinylmethyl)-4-(5,6-dichloro-1-indancarbonyl)-tetrahydro-1,4-thiazine hydrochloride |
r 86428 |
r-86428 |
thiomorpholine, 4-((5,6-dichloro-2,3-dihydro-1h-inden-1-yl)carbonyl)-3-(1-pyrrolidinylmethyl)-, monohydrochloride, (r-(r*,s*))- |
r-84761 |
r-86436 |
157824-23-2 (hcl) |
((s)-5,6-dichloro-2,3-dihydro-1h-inden-1-yl)((r)-3-(pyrrolidin-1-ylmethyl)thiomorpholino)methanone hydrochloride |
r-84760 hydrochloride |
DTXSID60935809 |
(5,6-dichloro-2,3-dihydro-1h-inden-1-yl){3-[(pyrrolidin-1-yl)methyl]thiomorpholin-4-yl}methanone--hydrogen chloride (1/1) |
[(1s)-5,6-dichloro-2,3-dihydro-1h-inden-1-yl]-[(3r)-3-(pyrrolidin-1-ylmethyl)thiomorpholin-4-yl]methanone;hydrochloride |
r84760 |
methanone, ((1s)-5,6-dichloro-2,3-dihydro-1h-inden-1-yl)((3r)-3-(1-pyrrolidinylmethyl)-4-thiomorpholinyl)-, hydrochloride (1:1) |
AKOS040749268 |
Research Excerpts
Dosage Studied
Excerpt | Relevance | Reference |
---|---|---|
" The plasma concentration of unchanged form after administration at a trace dosage amount was able to be monitored." | ( Quantitative analysis of R-84760, a selective kappa-opioid receptor agonist, in plasma by liquid chromatography with electrospray ionization tandem mass spectrometry. Kobayashi, N; Naganuma, H, 1999) | 0.3 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (66.67) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.10
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.10) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |