Page last updated: 2024-12-07

ponceau mx

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ponceau MX: RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

4-[(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonic acid : A naphthalenesulfonic acid that is naphthalene-2,7-disulfonic acid carrying additional hydroxy and (2,4-dimethylphenyl)diazenyl substituents at positions 3 and 4 respectively. The disodium salt is the biological stain 'acid red 26'. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID111804
CHEMBL ID1356392
CHEBI ID87104
SCHEMBL ID4068193
SCHEMBL ID8816124
SCHEMBL ID22799025
MeSH IDM0064757

Synonyms (123)

Synonym
NSC10458 ,
nsc-10458
c.i. 16150
NCGC00013108
xylidine ponceau 3rs
paper red hrr
naphthalene scarlet r
ponceau fr
lake ponceau
acid ponceau r
acilan ponceau rrl
kiton scarlet 2rc
scarlet rra
ponceau pxm
acid leather red kpr
calcocid scarlet 2r
ponceau nr
ponceau rr
amacid lake scarlet 2r
ponceau bna
acid scarlet 2r for lakes
ponceau rr type 8019
edicol supra ponceau r
ponceau 2rl
kiton ponceau r
colacid ponceau special
comacid scarlet 2r
acid ponceau 2rl(*disodium salt*)
acid leather scarlet irw
food red no. 101
ponceau 2r (biological stain)
acid leather scarlet irw(*disodium salt*)
scarlet 2r
ponceau 2rx
aizen ponceau rh
ponceau red
naphthalene lake scarlet r
ponceau 2r
lake scarlet 2rbn
neklacid red rr
ponceau rg
acid scarlet 2b
red r
fenazo scarlet 2r
naphthazine scarlet 2r
xylidine ponceau(*disodium salt*)
acetacid red j
acid scarlet
tertracid ponceau 2r
ponceau 2r extra a export
acidal ponceau g
calcolake scarlet 2r
scarlet 2rl bluish
hexacol ponceau 2r
ponceau r (biological stain)
ponceau 2re
xylidine ponceau
ponceaux mx
calcocid scarlet 2ril
new ponceau 4r
c.i. acid red 26, disodium salt
hispacid ponceau r
amacid scarlet 2r
2,7-naphthalenedisulfonic acid, 3-hydroxy-4-(2,4-xylylazo)-
ponceau mx
schultz no. 95
hexacol ponceau mx
xylidine ponceau 3rs(*disodium salt*)
acid scarlet 2rn
java ponceau 2r
scarlet 2rb
ponceau gr
xylidine red
acid scarlet 2rl
calcocid 2ril
disodium salt of 1-(2,4-xylylazo)-2-naphthol-3,6-disulfonic acid
acid leather red p2r
hidacid scarlet 2r
4-[(e)-(2,4-dimethylphenyl)azo]-3-hydroxy-naphthalene-2,7-disulfonic acid
red for lakes j
acid scarlet 2r
ponceau xylidine (biological stain)
kiton ponceau 2r
acid ponceau 2rl
acid scarlet 2r for lakes bluish
d and c red no. 5
acid scarlet 2bn
brilliant ponceau g
ponceau red r
certicol ponceau mxs
4-((2,4-dimethylphenyl)diazenyl)-3-hydroxy-2,7-naphthalenedisulfonic acid
ponceau rs
ponceau j
ahcocid fast scarlet r
lake scarlet r
c.i. food red 5
acid ponceau special
scarlet 2rl
disodium (2, 4-dimethylphenylazo)-2-hydroxynaphthalene-3,6-disulfonate
ponceau r
edicol ponceau rs
1-(2,4-xylylazo)-2-naphthol-3,6-disulfonic acid disodium salt
NCI10458
NCI60_000110
NCISTRUC1_001130
NCISTRUC2_001011
NCGC00096229-01
2,7-naphthalenedisulfonic acid, 4-((2,4-dimethylphenyl)azo)-3-hydroxy-
7481-49-4
CCG-37282
NCGC00013108-02
SCHEMBL4068193
CHEMBL1356392
SCHEMBL8816124
4-[(2,4-dimethylphenyl)diazenyl]-3-hydroxynaphthalene-2,7-disulfonic acid
acid red 26 (free acid form)
CHEBI:87104
1-(2,4-xylylazo)-2-naphthol-3,6-disulfonic acid
Q27159370
Q7227611
SCHEMBL22799025
4-[2-(2,4-dimethylphenyl)diazenyl]-3-hydroxy-2,7-naphthalenedisulfonic acid
DTXSID001144019

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" In this study, the toxicity of these dyes was assessed in a zebrafish model, and the underlying toxic mechanisms were investigated."( Toxicity induced by Basic Violet 14, Direct Red 28 and Acid Red 26 in zebrafish larvae.
Eilers, G; Li, CQ; Li, YQ; Liu, HC; Meng, FG; Ou, WB; Shen, B; Zhou, SM, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
carcinogenic agentA role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
cardiotoxic agentA role played by a chemical compound exihibiting itself through the ability to induce damage to the heart and cardiomyocytes.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (3)

ClassDescription
azobenzenesAny member of the wide class of molecules that share the core azobenzene structure, comprising two phenyl rings linked by a N=N double bond, which may have different functional groups extending from the rings.
naphthalenesulfonic acid
naphtholsAny hydroxynaphthalene derivative that has a single hydroxy substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (2)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency5.01190.011212.4002100.0000AID1030
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency0.07940.00137.762544.6684AID914; AID915
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's5 (41.67)24.3611
2020's2 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.81

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.81 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index5.19 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.81)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]