| Assay ID | Title | Year | Journal | Article |
|---|
| AID225212 | Tested for the change in body weight between day1 and 7 for murine solid tumor model C26 early stage that is subcutaneously implanted by the intravenous treatment at the dose of 10 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID228628 | Tested for medium tumor weight of treated /control animals x 100 (% T/C) for murine solid tumor model B16 early stage that is subcutaneously implanted by the intravenous treatment at the dose of 5 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID97886 | Cytotoxicity against L1210 tumor cell line, activity is expressed as K (inverse value of drug concentration) | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID225216 | Tested for medium tumor weight of treated /control animals x 100 (% T/C) for murine solid tumor model MA 16/C early stage that is subcutaneously implanted by the intravenous treatment at the dose of 5 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID225215 | Tested for the change in body weight between day1 and 7 for murine solid tumor model MA 16/C early stage that is subcutaneously implanted by the intravenous treatment at the dose of 5 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID96801 | In vitro cytotoxicity against L1210 cell line as concentration required for 50% inhibition of cell growth | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID154582 | In vivo T/C (survival time treated/survival time control x 100) was determined against P388 leukemia cells at 10 mg/Kg | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID225210 | Tested for medium tumor weight of treated /control animals x 100 (% T/C) for murine solid tumor model C26 early stage that is subcutaneously implanted by the intravenous treatment at the dose of 10 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID98986 | Antitumor activity against L1210 leukemia cells measured as range of death at 20 mg/kg; value may range from 14 to 25 | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID96956 | Antitumor activity against L1210 leukemia cells measured as percent increase in life span (% ILS) at 10 mg/kg | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID228629 | Tested for the change in body weight between day1 and 7 for murine solid tumor model B16 early stage that is subcutaneously implanted by the intravenous treatment at the dose of 5 mg/kg in 1-4 schedule | 1990 | Journal of medicinal chemistry, May, Volume: 33, Issue:5
| Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents. |
| AID98442 | Antitumor activity against L1210 leukemia cells measured as Median survival time at 20 mg/kg | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID212887 | Acute toxicity in mice (LD100) after i.p. administration | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| AID212886 | Acute toxicity in mice (LD0) after i.p. administration (highest nontoxic dose) | 1983 | Journal of medicinal chemistry, Feb, Volume: 26, Issue:2
| Antitumor amino-substituted pyrido[3',4':4,5]pyrrolo[2,3-g]isoquinolines and pyrido[4,3-b]carbazole derivatives: synthesis and evaluation of compounds resulting from new side chain and heterocycle modifications. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |