Assay ID | Title | Year | Journal | Article |
AID1578535 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring relative abundance measured after preserving compound in amber vial con | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578528 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring maximum absorbance units measured after preserving compound in amber vi | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578530 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring maximum absorbance units measured after preserving compound in amber vi | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578529 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring maximum absorbance units measured after preserving compound in amber vi | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578537 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring relative abundance measured after preserving compound in amber vial con | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578539 | Stability of compound assessed as shelf life measured after preserving compound in amber vial containing 95% CH3CN and 5% H2O followed by drying using N2 stream and later punged-with argon in dark desiccator under vacuum for 24 hrs | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578536 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring relative abundance measured after preserving compound in amber vial con | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578534 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring relative abundance measured after preserving compound in amber vial con | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578525 | Cytotoxicity against human PANC1 cells assessed as reduction in cell viability incubated for 3 days by tryphan blue dye based assay | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578533 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by relative abundance measured after preserving compound in amber vial containing 95 | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578540 | Stability of compound assessed as shelf life measured after preserving compound in amber vial containing 95% CH3CN and 5% H2O followed by drying using N2 stream and later punged-with argon followed by exposure to 4 degC for 24 hrs | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578532 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring maximum absorbance units measured after preserving compound in amber vi | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578531 | Drug degradation assessed as methyl N-[(E)-8-[4-[(2E)-hexa-2,5-dienyl]-1,3-thiazol-2-yl]-3,7-dihydroxy-3-(hydroxymethyl)-8-methylnon-4-enyl]carbamate metabolite formation by measuring maximum absorbance units measured after preserving compound in amber vi | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578527 | Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 3 days by tryphan blue dye based assay | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
AID1578526 | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 3 days by tryphan blue dye based assay | 2020 | ACS medicinal chemistry letters, Feb-13, Volume: 11, Issue:2
| Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8 |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |