Page last updated: 2024-10-24

peptide YY receptor activity

Definition

Target type: molecularfunction

Combining with gut peptide YY to initiate a change in cell activity. [PMID:9315606]

Proteins (3)

ProteinDefinitionTaxonomy
Neuropeptide Y receptor type 5A neuropeptide Y receptor type 5 that is encoded in the genome of human. [PRO:WCB, UniProtKB:Q15761]Homo sapiens (human)
Neuropeptide Y receptor type 2A neuropeptide Y receptor type 2 that is encoded in the genome of human. [PRO:WCB, UniProtKB:P49146]Homo sapiens (human)
Neuropeptide Y receptor type 1A neuropeptide Y receptor type 1 that is encoded in the genome of human. [PRO:WCB, UniProtKB:P25929]Homo sapiens (human)

Compounds (18)

CompoundDefinitionClassesRoles
benextraminebenextramine: RN given refers to parent cpd
econazole1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole : A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group.

econazole : A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections.

Econazole: An imidazole derivative that is commonly used as a topical antifungal agent.
dichlorobenzene;
ether;
imidazoles;
monochlorobenzenes
N-(4-ethoxyphenyl)-4-[hydroxy(diphenyl)methyl]-1-piperidinecarbothioamidediarylmethane
2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamideoxadiazole;
ring assembly
3,5-dimethyl-4-[(4-methylphenyl)sulfonyl-phenylmethyl]isoxazolesulfonic acid derivative
bibp 3226BIBP 3226: a selective non-peptide neuropeptide Y Y1 receptor antagonist; structure given in first source; BIBP-3435 is the S-enantiomer
cgp 71683 anaphthalenes;
sulfonic acid derivative
n-(4-((4-(dimethylamino)quinazolin-2-yl)amino)cyclohexyl)-3,4-difluorobenzamide hydrochloride
4-n-butyl-1-(4-(2-methylphenyl)-4-oxo-1-butyl)-piperidine hydrogen chloride
bms 193885
jnj-5207787N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-(1-(2-cyclopentyl-ethyl)-piperidin-4yl)acrylamide: structure in first source
mk-0557
neuropeptide y (24-36) amide, n-acetyl-(leu(28,31))-neuropeptide Y (24-36) amide, N-acetyl-(Leu(28,31))-: a presynaptic (Y2) receptor-specific neuropeptide Y analog
neuropeptide yNeuropeptide Y: A 36-amino acid peptide present in many organs and in many sympathetic noradrenergic neurons. It has vasoconstrictor and natriuretic activity and regulates local blood flow, glandular secretion, and smooth muscle activity. The peptide also stimulates feeding and drinking behavior and influences secretion of pituitary hormones.
bombesin
lu aa33810
jnj-31020028
nitd 609NITD 609: an antimalarial and coccidiostat; structure in first source