Page last updated: 2024-11-07

km 200

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Grotan BK: contains 1,3,5-tris(hydroxyethyl)hexahydrotriazine; releases formaldehyde; bactericidal agent in coolant liquids; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID104556
CHEMBL ID3561636
SCHEMBL ID125784
MeSH IDM0058448

Synonyms (90)

Synonym
4719-04-4
hexahydro-1,5-tris(hydroxyethyl)triazine
1,5-tris(2-hydroxyethyl)hexahydro-s-triazine
onyxide 200
grotan bk
grotan hd
grotan
nsc-516387
hexahydro-1,5-tris(2-hydroxyethyl)-s-triazine
s-triazine-1,5(2h,4h,6h)-triethanol
hexahydro-1,5-tris(2-hydroxypropyl)-s-triazine
rancidity control agent
1,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
1,5-triazine-1,3,5(2h,4h,6h)-triethanol
kalpur te
grotan b
nsc516387
hexahydro-1,5-tris(2-hydroxyethyl)triazine
1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine
roksol t 1-7
km 200 (alcohol)
brn 0124982
1,3,5-tris(2-hydroxyethyl)hexahydro-s-triazine
actane
ottaform 204
1,3,5-tris(hydroxy-ethyl)s-hexahydrotriazine
triazinetriethanol
hexahydro-1,3,5-triazine-1,3,5-triethanol
2,2',2''-(hexahydro-1,3,5-triazine-1,3,5-triyl)triethanol
hexahydro-1,3,5-tris(2-hydroxyethyl)-s-triazine
hexahydro-1,3,5-tris(hydroxyethyl)triazine
ccris 6246
eta 75
s-triazine-1,3,5(2h,4h,6h)-triethanol
caswell no. 481c
busan 1060
einecs 225-208-0
nsc 516387
epa pesticide chemical code 083301
2,2',2''-(1,3,5-triazinane-1,3,5-triyl)triethanol
1,3,5-triazine-1,3,5(2h,4h,6h)-triethanol
bactraclean
triadine 3
hexahydro-1,3,5-tri(2-hydroxyethyl)-s-triazine
1,3,5-tris(2-hydroxyethyl)-1,3,5-triazacyclohexane
n,n',n''-tris(2-hydroxyethyl)hexahydro-s-triazine
busan 1506
s-triazine-1,3,5-triethanol
permachem ob 2
protectol ht
surcide p
surcide d
bioban gk
cobate c
nipacide bk
acticide gr
2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanol
hexahydro-1,3,5-tris(hydroxyethyl)-s-triazine
ec 225-208-0
ou2jeb22ie ,
km-200
unii-ou2jeb22ie
4-26-00-00010 (beilstein handbook reference)
km 200
1,3,5-trihydroxyethylhexahydrotriazine
FT-0675394
SCHEMBL125784
1,3,5-tris-hydroxyethyl perhydro-s-triazine
1,3,5-tris(2-hydroxyethyl)perhydro-s-triazine
1,3,5-tris(2-hydroxyethyl)perhydro-s-tria-zine
tris(n-hydroxyethyl) hexahydrotriazine
tris(n-hydroxyethyl) hexahydrotriazine [inci]
eta-75
tris(.beta.-hydroxyethyl)hexahydro-s-triazine
AKOS024462548
dtxcid405394
tox21_303727
cas-4719-04-4
NCGC00357283-01
dtxsid7025394 ,
hexahydro-1,3,5-tris(2-hydroxyethyl)triazine
tris-hydroxyethyl-hexahydro-s-triazine
miliden x-2
CHEMBL3561636
appolo-207
mfcd01678788
Q27285845
CS-W018942
c9h21n3o3
PD056846

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In addition, as a positive control, benzidine at a total dosage of 409."( An evaluation of the mutagenicity of the cutting oil preservative Grotan BK.
Palmer, AK; Richardson, JC; Urwin, C, 1976
)
0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
RAR-related orphan receptor gammaMus musculus (house mouse)Potency27.30600.006038.004119,952.5996AID1159521
GLI family zinc finger 3Homo sapiens (human)Potency0.24340.000714.592883.7951AID1259369
AR proteinHomo sapiens (human)Potency43.27710.000221.22318,912.5098AID1259243
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency68.58960.003041.611522,387.1992AID1159552; AID1159555
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 67.75

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index67.75 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.67 (4.65)
Search Engine Demand Index107.09 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (67.75)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies2 (16.67%)4.05%
Observational0 (0.00%)0.25%
Other10 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]