Compounds > glycerophosphoserine
Page last updated: 2024-11-10

glycerophosphoserine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

glycerophosphoserine: RN given refers to (L-serine)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

glycerol 1-phosphoserine : A L-serine derivative consisting of L-serine having a 1-glycerophospho group attached to the side-chain hydroxy function. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID3081457
CHEBI ID62013
MeSH IDM0185385

Synonyms (15)

Synonym
l-serine, 2,3-dihydroxypropyl hydrogen phosphate (ester)
glycerophosphoserine
l-serine 2,3-dihydroxypropyl hydrogen phosphate
1-glycerophosphoserine
glycerol 1-phosphoserine
o-[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]-l-serine
CHEBI:62013
l-serine 1-phosphoglycerol
glycero-1-phosphoserine
26289-09-8
glycerylphosphoserine
Q27131526
C22237
o-[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]serine
DTXSID60949148

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The biocompatibility of synthesized segmented polyurethanes was then investigated by platelet-rich plasma contact studies and related scanning electron microscopy (SEM) photographs for blood compatibility and cytotoxicity assay (MTT test) on material elution to assess the effect of any toxic leachables on cellular viability."( Synthesis, platelet adhesion and cytotoxicity studies of new glycerophosphoryl-containing polyurethanes.
D'Arrigo, P; Giordano, C; Macchi, P; Malpezzi, L; Pedrocchi-Fantoni, G; Servi, S, 2007)		0.34
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
glycerol 1-phosphodiesterA monoester of glycerophosphoric acid where R is an organyl group.
L-serine derivativeA proteinogenic amino acid derivative resulting from reaction of L-serine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-serine by a heteroatom.
non-proteinogenic L-alpha-amino acidAny L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's6 (54.55)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.32

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.32 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.32)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (18.18%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (81.82%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
phosphoserine
Phosphoserine: The phosphoric acid ester of serine.		10.42110non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative		human metabolite
choline
[no description available]		3.1310cholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
phosphorylcholine
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.. phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.		3.1410phosphocholinesallergen;
epitope;
hapten;
human metabolite;
mouse metabolite
chloroform
Chloroform: A commonly used laboratory solvent. It was previously used as an anesthetic, but was banned from use in the U.S. due to its suspected carcinogenicity.. chloroform : A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.		2.0810chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
glycerylphosphorylcholine
Glycerylphosphorylcholine: A component of PHOSPHATIDYLCHOLINES or LECITHINS, in which the two hydroxy groups of GLYCEROL are esterified with fatty acids. (From Stedman, 26th ed)		2.9340glycerophosphocholine
arginyl-glycyl-aspartyl-serine
arginyl-glycyl-aspartyl-serine: corresponds to cell attachment site of fibronectin; located near carboxyl-terminal region of alpha-chain of fibrinogen; inhibits platelet aggregation & fibrinogen binding to activated platelets		1.9810
rges peptide
[no description available]		1.9810
glycerophosphoethanolamine
glycerol 3-phosphoethanolamine: a membrane lipid degradation product		4.8760phosphoethanolamine;
sn-glycerol 3-phosphates
glycerophosphoinositol 4,5-bisphosphate
glycerophosphoinositol 4,5-bisphosphate: do not confuse with phosphatidylinositols which have fatty acids esterified at the C-1 and C-2 hydroxyl groups of glycerol		2.0410
diglycerol phosphate
diglycerol phosphate: protein stabilizer isolated from Archaeoglobus fulgidus. glycerophosphoglycerol(1-) : An organophosphate oxoanion that is the conjugate base of glycerophosphoglycerol; major species at pH 7.3.		2.4420organophosphate oxoanion
glycolipids
[no description available]		3.8430
ConditionIndicatedRelationship StrengthStudiesTrials
Edema-Proteinuria-Hypertension Gestosis
[description not available]		02.0710
Pre-Eclampsia
A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.		02.0710
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		02.0710