Assay ID | Title | Year | Journal | Article |
AID683076 | Inhibition of human ABCB1 pump expressed in mouse L5178 cells assessed as fluorescence activity ratio at 20 uM for 10 mins by flow cytometry relative to control | 2012 | Journal of medicinal chemistry, Jun-14, Volume: 55, Issue:11
| Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter. |
AID683088 | Inhibition of human ABCB1 expressed in mouse L5178 cells assessed as 95% inhibition of cell proliferation at compound-doxorubicin ratio of 40.8:1 after 48 hrs by MTT assay | 2012 | Journal of medicinal chemistry, Jun-14, Volume: 55, Issue:11
| Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter. |
AID380242 | Inhibition of DMBA-induced/TPA-promoted carcinogenesis in mouse assessed as number of mouse bearing papillomas at 85 nmol administered twice weekly after 1 week of initiation for 17 weeks | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380236 | Cytotoxicity against human Raji cells assessed as cell viability at 100 molar ratio after 48 hrs | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380234 | Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio after 48 hrs | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380230 | Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells at 1000 molar ratio relative to control | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380240 | Inhibition of DMBA-induced/TPA-promoted carcinogenesis in mouse assessed as number of mouse bearing papillomas at 85 nmol administered twice weekly after 1 week of initiation for 8 weeks | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380233 | Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells at 10 molar ratio relative to control | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380237 | Cytotoxicity against human Raji cells assessed as cell viability at 10 molar ratio after 48 hrs | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380239 | Inhibition of DMBA-induced/TPA-promoted carcinogenesis in mouse assessed as number of skin papillomas per mouse at 85 nmol administered twice weekly after 1 week of initiation for 20 weeks | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380235 | Cytotoxicity against human Raji cells assessed as cell viability at 500 molar ratio after 48 hrs | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380232 | Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells at 100 molar ratio relative to control | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID380241 | Inhibition of DMBA-induced/TPA-promoted carcinogenesis in mouse assessed as number of mouse bearing papillomas at 85 nmol administered twice weekly after 1 week of initiation for 10 weeks | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID431525 | Binding affinity to ecdysone receptor ligand binding domain in Drosophila melanogaster assessed as number of hydrogen bonds formed | 2009 | Bioorganic & medicinal chemistry, Aug-15, Volume: 17, Issue:16
| Evaluation of hydrogen bonds of ecdysteroids in the ligand-receptor interactions using a protein modeling system. |
AID683085 | Inhibition of human ABCB1 expressed in mouse L5178 cells assessed as 75% inhibition of cell proliferation at compound-doxorubicin ratio of 40.8:1 after 48 hrs by MTT assay | 2012 | Journal of medicinal chemistry, Jun-14, Volume: 55, Issue:11
| Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter. |
AID380238 | Inhibition of DMBA-induced/TPA-promoted carcinogenesis in mouse assessed as number of skin papillomas per mouse at 85 nmol administered twice weekly after 1 week of initiation for 10 weeks | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
AID683082 | Inhibition of human ABCB1 expressed in mouse L5178 cells assessed as 50% inhibition of cell proliferation at compound-doxorubicin ratio of 40.8:1 after 48 hrs by MTT assay | 2012 | Journal of medicinal chemistry, Jun-14, Volume: 55, Issue:11
| Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter. |
AID380231 | Inhibition of 12-O-tetradecanoylphorbol-13-acetate induced EBV-early antigen activation in human Raji cells at 500 molar ratio relative to control | 1999 | Journal of natural products, Jul, Volume: 62, Issue:7
| Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |