Page last updated: 2024-12-06

aphos

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID Source	ID
PubMed CID	53051
SCHEMBL ID	767190
MeSH ID	M0105623

Synonyms (11)

Synonym
(1-(acetyloxy)-2,2,2-trichloroethyl)phosphonic acid diphenyl ester
aphos
o,o-diphenyl (1-acetoxy-2,2,2-trichloroethyl)phosphonate
phosphonic acid, (1-(acetyloxy)-2,2,2-trichloroethyl)-, diphenyl ester
(2,2,2-trichloro-1-diphenoxyphosphorylethyl) acetate
74548-80-4
phosphonic acid,[1-(acetyloxy)-2,2,2-trichloroethyl]-, diphenyl ester (9ci)
SCHEMBL767190
DTXSID90996069
2,2,2-trichloro-1-(diphenoxyphosphoryl)ethyl acetate
o,o-diphenyl(1-acetoxy-2,2,2-trichloroethyl)phosphonate

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	9 (81.82)	18.7374
1990's	1 (9.09)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (9.09)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 44.28

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	44.28 (24.57)
Research Supply Index	2.56 (2.92)
Research Growth Index	4.28 (4.65)
Search Engine Demand Index	62.09 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (44.28)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	12 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
dimethyl sulfoxide Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.	1.97	1	sulfoxide; volatile organic compound	alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger
nitrates Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.	1.96	1	monovalent inorganic anion; nitrogen oxoanion; reactive nitrogen species
oxalic acid Oxalic Acid: A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent.. oxalic acid : An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.	1.96	1	alpha,omega-dicarboxylic acid	algal metabolite; human metabolite; plant metabolite
dimethyl phthalate dimethyl phthalate: used as plasticizer in computer mouse; structure	1.96	1	diester; methyl ester; phthalate ester
cadmium Cadmium: An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.. elemental cadmium : An element in the zinc group of the periodic table with atomic number 48, atomic mass 112, M.P. 321degreeC, and B.P. 765degreeC). An odourless, tasteless, and highly poisonous soft, ductile, lustrous metal with electropositive properties. It has eight stable isotopes: (106)Cd, (108)Cd,(110)Cd, (111)Cd, (112)Cd, (113)Cd, (114)Cd and (116)Cd, with (112)Cd and (114)Cd being the most common.	1.96	1	cadmium molecular entity; zinc group element atom
lead nitrate lead nitrate: RN given refers to unspecified lead nitrate	1.96	1	inorganic nitrate salt; lead coordination entity
cadmium nitrate cadmium nitrate: RN given refers to parent cpd. cadmium nitrate : An inorganic nitrate salt having Cd(2+) as the counterion.	1.96	1	cadmium salt; inorganic nitrate salt	carcinogenic agent; genotoxin; hepatotoxic agent
lead Lead: A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.	1.96	1	carbon group element atom; elemental lead; metal atom	neurotoxin
crotoxyphos crotoxyphos: structure	1.96	1	carboxylic ester
oxalates Oxalates: Derivatives of OXALIC ACID. Included under this heading are a broad variety of acid forms, salts, esters, and amides that are derived from the ethanedioic acid structure.	1.96	1
acid phosphatase Acid Phosphatase: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.	1.97	1

Condition	Relationship Strength	Studies
Anoxemia [description not available]	2.6	1
Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms.	2.6	1
Palsy [description not available]	2.37	2
Paralysis A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)	2.37	2

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