ap-10 and Neoplasms

ap-10 has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for ap-10 and Neoplasms

ArticleYear
Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of andrographolide.
    Bioorganic & medicinal chemistry letters, 2013, Dec-01, Volume: 23, Issue:23

    In the present study, andrographolide (Andro, 1) derivatives were screened to identify potent inhibitors against tumor-cell migration and invasion, and associated structure-activity relationships were studied. Compared to 1, compounds 8a-8d exhibited more potent activities against migration in SGC-7901, PC-3, A549, HT-29 and Ec109 cell lines. Improved activities against tumor-cell migration and invasion were proved to be associated with the down-regulation of MMPs.

    Topics: Cell Movement; Cell Proliferation; Diterpenes; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Neoplasms; Structure-Activity Relationship

2013