| Assay ID | Title | Year | Journal | Article |
|---|
| AID53553 | In vitro inhibition of cytochrome P450 19A1 | 1991 | Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
| Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. |
| AID269149 | Inhibition of rat microsomal 17,20-lyase component of P450-17alpha | 2006 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 16, Issue:15
| Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). |
| AID429611 | Inhibition of aromatase | 2009 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 19, Issue:16
| Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)). |
| AID282900 | Inhibition of human placental microsome CYP19 | 2005 | Journal of medicinal chemistry, Nov-17, Volume: 48, Issue:23
| Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach. |
| AID459283 | Inhibition of human CYP11B1 expressed in chinese hamster V79 cells | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). |
| AID269148 | Inhibition of rat microsomal 17-alpha-hydroxylase component of P450-17alpha | 2006 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 16, Issue:15
| Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). |
| AID459282 | Inhibition of human CYP11B2 expressed in chinese hamster V79 cells | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). |
| AID615415 | Inhibition of aromatase using 7-methoxy-4-trifluoromethyl coumarin as substrate after 30 mins by fluorescence-based colorimetric analysis | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9
| Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors. |
| AID459284 | Selectivity ratio of IC50 for human CYP11B2 to IC50 human CYP11B1 | 2010 | Journal of medicinal chemistry, Feb-25, Volume: 53, Issue:4
| Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |