cerberin : A cardenolide glycoside that is the 2'-acetyl derivative of neriifolin. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 10031063 |
| CHEMBL ID | 554969 |
| CHEBI ID | 75049 |
| SCHEMBL ID | 868106 |
| MeSH ID | M0049806 |
| Synonym |
|---|
| 3-((2-o-acetyl-6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxycard-20(22)-endolide (3beta,5beta)- |
| 3-((4-o-acetyl-6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxy-(3beta,5beta)-card-20(22)-enolide |
| 5-beta-card-20(22)-enolide, 3-beta-((6-deoxy-3-o-methyl-beta-l-glucopyranosyl)oxy)-14-hydroxy-, 4'-acetate |
| card-20(22)-endolide, 3-((2-o-acetyl-6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy)-14-hydroxy-, (3beta,5beta)- |
| acetylneriifolin [german] |
| pveneniferin [german] |
| neriifolin-monoacetat [german] |
| cerberin |
| 2'-acetylneriifolin |
| CHEMBL554969 |
| chebi:75049 , |
| C19984 |
| 3beta-o-(l-2'-o-acetylthevetosyl)-14beta-hydroxy-5beta-card-20(22)-enolide |
| (3beta,5beta)-3-[(2-o-acetyl-6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide |
| acetylneriifolin |
| kw5a155s64 , |
| 25633-33-4 |
| neriifolin-monoacetat |
| unii-kw5a155s64 |
| pveneniferin |
| veneniferin |
| SCHEMBL868106 |
| neriifolin 2'-acetate |
| neriifolin 2'-acetate [mi] |
| card-20(22)-enolide, 3-((2-o-acetyl-6-deoxy-3-o-methyl-.alpha.-l-glucopyranosyl)oxy)-14-hydroxy-, (3.beta.,5.beta.)- |
| monoacetylneriifolin |
| card-20(22)-enolide, 3-[(2-o-acetyl-6-deoxy-3-o-methyl-.alpha.-l-glucopyranosyl)oxy]-14-hydroxy-, (3.beta.,5.beta.)- |
| DTXSID30893922 |
| Q5063899 |
| 3beta-o-(l-2'-o-acetyl thevetoyl)-14beta-hydroxy-5beta-card-20(22)-enolide |
| [(2r,3s,4r,5s,6s)-5-hydroxy-2-[[(3s,5r,8r,9s,10s,13r,14s,17r)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2h-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-methoxy-6-methyloxan-3-yl] acetate |
| [(2s,3s,4s,5s,6r)-5-hydroxy-6-[[(3s,5r,8r,9s,10s,13r,14s,17r)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2h-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-methoxy-2-methyloxan-3-yl] acetate |
| (3beta,5beta)-3-[(2-o-acetyl-6-deoxy-3-o-methyl-alpha-l-glucopyranosyl)oxy]-14-hydroxy-card-20(22)-enolide |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Cerberin has a mechanism of action similar to digoxin; hence, Cerbera odollam toxicity manifests similar to acute digoxin poisoning." | ( Cerbera odollam toxicity: A review. Fatima, H; Fatima, TQ; Hussain, SA; Luis, SA; Madadin, M; Menezes, RG; Pasha, SB; Ram, P; Senthilkumaran, S; Siddiqi, TJ; Usman, MS, 2018) | 1.2 |
| Role | Description |
|---|---|
| antineoplastic agent | A substance that inhibits or prevents the proliferation of neoplasms. |
| metabolite | Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| cardenolide glycoside | Any member of the class of cardenolides with glycosyl residues attached to position 3. |
| monosaccharide derivative | A carbohydrate derivative that is formally obtained from a monosaccharide. |
| acetate ester | Any carboxylic ester where the carboxylic acid component is acetic acid. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID421891 | Insecticidal activity against Ostrinia nubilalis | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3 | Plant seeds as sources of potential industrial chemicals, pharmaceuticals, and pest control agents. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (36.58) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (40.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3 (60.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||