Compounds > viomellein
Page last updated: 2024-12-10

viomellein

Description

viomellein: metabolite of Penicillium viridicatum causing hepatic lesions in mice [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3033108
MeSH IDM0061727

Synonyms (19)

Synonym
8-(3,4-dihydro-9,10-dihydroxy-7-methoxy-3-methyl-1-oxo-1h-naphtho(2,3-c)pyran-8-yl)-3,4-dihydro-6- hydroxy-9-methoxy-3-methyl-1h-naphtho(1,2-c)pyran-1,7,10-trione
viomellein
brn 4630536
(8,8'-bi-1h-naphtho(2,3-c)pyran)-1,1',6,9-tetrone, 3,3',4,4'-tetrahydro-7,7'-dimethoxy-3,3'-dimethyl-9',10,10'-trihydroxy-, (r-(r*,r*))-
(3r)-8-[(3r)-9,10-dihydroxy-7-methoxy-3-methyl-1-oxo-3,4-dihydrobenzo[g]isochromen-8-yl]-10-hydroxy-7-methoxy-3-methyl-3,4-dihydrobenzo[g]isochromene-1,6,9-trione
55625-78-0
unii-9r5rc7qx9b
5-19-07-00211 (beilstein handbook reference)
9r5rc7qx9b ,
AKOS030213230
DTXSID00204162
mfcd01740396
(8,8'-bi-1h-naphtho(2,3-c)pyran)-1,1',6,9-tetrone, 3,3',4,4'-tetrahydro-9',10,10'-trihydroxy-7,7'-dimethoxy-3,3'-dimethyl-, (r-(r*,r*))-
(3r,3'r)-3,3',4,4'-tetrahydro-9',10,10'-trihydroxy-7,7'-dimethoxy-3,3'-dimethyl(8,8'-bi-1h-naphtho(2,3-c)pyran)-1,1',6,9-tetrone
(8,8'-bi-1h-naphtho(2,3-c)pyran)-1,1',6,9-tetrone, 3,3',4,4'-tetrahydro-9',10,10'-trihydroxy-7,7'-dimethoxy-3,3'-dimethyl-, (3r,3'r)-
[8,8'-bi-1h-naphtho[2,3-c]pyran]-1,1',6,9-tetrone,3,3',4,4'-tetrahydro-9',10,10'-trihydroxy-7,7'-dimethoxy-3,3'-dimethyl-,(3r,3'r)-
Q2527503
8-(3,4-dihydro-9,10-dihydroxy-7-methoxy-3-methyl- 1-oxo-1h-naphtho(2,3-c)pyran-8-yl)-3,4-dihydro-6- hydroxy-9-methoxy-3-methyl-1h-naphtho(1,2-c)pyran- 1,7,10-trione
brn4630536

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (45.45)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.72 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.57 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
xanthine
7H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-7 is protonated.. 9H-xanthine : An oxopurine in which the purine ring is substituted by oxo groups at positions 2 and 6 and N-9 is protonated.		1.9910xanthineSaccharomyces cerevisiae metabolite
xanthomegnin
xanthomegnin: pigment isolated from pathogenic fungus, Microsporum cookei; also Penicillium viridicatum; structure		3.4880
viridicatin
viridicatin: structure. viridicatin : A hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae.		1.9910hydroxyquinolineantibacterial agent;
Aspergillus metabolite;
marine metabolite;
Penicillium metabolite
aurofusarin
aurofusarin: from Fusarium graminearum; structure given in first source		2.2110organic heterotricyclic compound;
organooxygen compound
ochratoxin a
ochratoxin A: structure in first source & in Merck, 9th ed, #6549. ochratoxin A : A phenylalanine derivative resulting from the formal condensation of the amino group of L-phenylalanine with the carboxy group of (3R)-5-chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxylic acid (ochratoxin alpha). It is among the most widely occurring food-contaminating mycotoxins, produced by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium verrucosum.		1.9610isochromanes;
monocarboxylic acid amide;
N-acyl-L-phenylalanine;
organochlorine compound;
phenylalanine derivative		Aspergillus metabolite;
calcium channel blocker;
carcinogenic agent;
mycotoxin;
nephrotoxin;
Penicillium metabolite;
teratogenic agent
ergosterol
[no description available]		6.98103beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols		fungal metabolite;
Saccharomyces cerevisiae metabolite
naphthoquinones
Naphthoquinones: Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.		3.69100
chiniofon
Hydroxyquinolines: The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.		1.9910
brevianamide a
brevianamide A: metabolite of Penicillium viridicatum; structure		6.9810
citrinin
Citrinin: Antibiotic and mycotoxin from Aspergillus niveus and Penicillium citrinum.		1.9610
ConditionIndicatedRelationship StrengthStudiesTrials
Swine Diseases
Diseases of domestic swine and of the wild boar of the genus Sus.		01.9610
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		01.9610
Acute Liver Injury, Drug-Induced
[description not available]		01.9510
Chemical and Drug Induced Liver Injury
A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.		01.9510
chemdatabank.com