Page last updated: 2024-11-07

valanimycin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

valanimycin: from a streptomycete; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

valanimycin : An azoxy compound that is acrylic acid in which the olefinic hydrogen at position 2 has been replaced by an isobutyl-ONN-azoxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID127995
CHEMBL ID4782825
CHEBI ID133621
MeSH IDM0138977

Synonyms (10)

Synonym
2-propenoic acid, 2-((2-methylpropyl)-onn-azoxy)-
2-(isobutyl-(onn)azoxy)acrylic acid
acrylic acid, 2-(isobutyl-(onn)azoxy)-
valanimycin
CHEBI:133621
101961-60-8
2-[(2-methylpropyl)-onn-azoxy]acrylic acid
2-[(2-methylpropyl)-onn-azoxy]prop-2-enoic acid
1-carboxyethenylimino-(2-methylpropyl)-oxidoazanium
CHEMBL4782825

Research Excerpts

Overview

Valanimycin is an unstable oil at room temperature and active against some Gram-positive and Gram-negative bacteria. It prolongs the life span of mice inoculated with Ehrlich carcinoma or L1210.

ExcerptReferenceRelevance
"Valanimycin is an unstable oil at room temperature and active against some Gram-positive and Gram-negative bacteria, mouse leukemia L1210 cells in cultures, and prolongs the life span of mice inoculated with Ehrlich carcinoma or L1210."( Isolation and properties of valanimycin, a new azoxy antibiotic.
Abe, V; Hamada, M; Hori, M; Iinuma, H; Masuda, T; Naganawa, H; Umezawa, H; Yamagishi, Y; Yamato, M, 1986
)
1.29
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1683147Antimicrobial activity against Staphylococcus aureus
AID1718303Antibacterial activity against Escherichia coli BE1121 by paper disc-agar diffusion method2020Journal of natural products, 11-25, Volume: 83, Issue:11
Chemistry and Biology of Natural Azoxy Compounds.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (17.65)18.7374
1990's3 (17.65)18.2507
2000's7 (41.18)29.6817
2010's1 (5.88)24.3611
2020's3 (17.65)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.18

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.18 (24.57)
Research Supply Index2.89 (2.92)
Research Growth Index4.77 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.18)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (5.88%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (94.12%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]