Page last updated: 2024-12-07
valanimycin
Description
valanimycin: from a streptomycete; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
valanimycin : An azoxy compound that is acrylic acid in which the olefinic hydrogen at position 2 has been replaced by an isobutyl-ONN-azoxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
Synonyms (10)
| Synonym |
|---|
| 2-propenoic acid, 2-((2-methylpropyl)-onn-azoxy)- |
| 2-(isobutyl-(onn)azoxy)acrylic acid |
| acrylic acid, 2-(isobutyl-(onn)azoxy)- |
| valanimycin |
| CHEBI:133621 |
| 101961-60-8 |
| 2-[(2-methylpropyl)-onn-azoxy]acrylic acid |
| 2-[(2-methylpropyl)-onn-azoxy]prop-2-enoic acid |
| 1-carboxyethenylimino-(2-methylpropyl)-oxidoazanium |
| CHEMBL4782825 |
Research Excerpts
Overview
Valanimycin is an unstable oil at room temperature and active against some Gram-positive and Gram-negative bacteria. It prolongs the life span of mice inoculated with Ehrlich carcinoma or L1210.
| Excerpt | Reference | Relevance |
|---|
| "Valanimycin is an unstable oil at room temperature and active against some Gram-positive and Gram-negative bacteria, mouse leukemia L1210 cells in cultures, and prolongs the life span of mice inoculated with Ehrlich carcinoma or L1210." | ( Isolation and properties of valanimycin, a new azoxy antibiotic.
Abe, V; Hamada, M; Hori, M; Iinuma, H; Masuda, T; Naganawa, H; Umezawa, H; Yamagishi, Y; Yamato, M, 1986) | 1.29 |
Research
Studies (17)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 3 (17.65) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.18
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 21.18 (24.57) | | Research Supply Index | 2.89 (2.92) | | Research Growth Index | 4.77 (4.65) | | Search Engine Demand Index | 18.60 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (5.88%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 16 (94.12%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |