Compounds > nk 5
Page last updated: 2024-11-12

nk 5

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

NK 5: antioxidant containing divalent cations of iron, manganese, & cobalt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16219292
CHEMBL ID1989021
CHEBI ID51502
MeSH IDM0057955

Synonyms (15)

Synonym
CHEBI:51502 ,
NSC34391 ,
1,1'-diethylquino-(4)-carbocyanine iodide
cryptocyanine o.a. 2
nk 5
cryptocyanine iodide
kryptocyanine iodide
nsc-34391
1,4'-carbocyanine iodide
eastman 1334
kryptocyanine
kryptocyanin
1,4'-quinocarbocyanine iodide
nk 5 (dye)
CHEMBL1989021
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
fluorochromeA fluorescent dye used to stain biological specimens.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
quinolinesA class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring.
organic iodide salt
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID658163Stabilization of DNA duplex hairpin structure assessed as change in melting temperature at 1 uM by FRET assay2012Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries.
AID658162Stabilization of human G-quadruplex F21T assessed as change in melting temperature at 1 uM by FRET assay2012Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries.
AID658164Stabilization of human G-quadruplex F21T assessed as change in melting temperature at 5 uM by FRET assay2012Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 47.64

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index47.64 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index69.20 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (47.64)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.0310alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
1-propanol
1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.. propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.		2.0310propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
tolonium chloride
Tolonium Chloride: A phenothiazine that has been used as a hemostatic, a biological stain, and a dye for wool and silk. Tolonium chloride has also been used as a diagnostic aid for oral and gastric neoplasms and in the identification of the parathyroid gland in thyroid surgery.. tolonium chloride : An organic chloride salt having 3-amino-7-(dimethylamino)-2-methylphenothiazin-5-ium (tolonium) as the counterion. It is a blue nuclear counterstain that can be used to demonstrate Nissl substance and is also useful for staining mast cell granules, both in metachromatic and orthochromatic techniques.		2.0710
dequalinium chloride
dequalinium chloride : An organic chloride salt that is the dichloride salt of dequalinium.		2.0710organic chloride saltantifungal agent;
antineoplastic agent;
antiseptic drug;
mitochondrial NADH:ubiquinone reductase inhibitor
Berberine chloride (TN)
[no description available]		2.0710organic molecular entity
acodazole
[no description available]		2.0710
nsc 38280
[no description available]		2.0710
taspine
taspine: RN given refers to parent cpd; structure		2.0710
nsc 314622
NSC 314622: structure in first source		2.0710
carbocyanines
Carbocyanines: Compounds that contain three methine groups. They are frequently used as cationic dyes used for differential staining of biological materials.		4.2550cyanine dye;
organic iodide salt		fluorochrome
braco-19
BRACO-19: structure in first source		2.0710acridines;
N-alkylpyrrolidine
ConditionIndicatedRelationship StrengthStudiesTrials
Herpes Simplex Virus Infection
[description not available]		03.5210
B Virus Infection
[description not available]		03.5210
Herpes Simplex
A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)		03.5210