Page last updated: 2024-11-12
nk 5
Description
NK 5: antioxidant containing divalent cations of iron, manganese, & cobalt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
Synonyms (15)
| Synonym |
|---|
| CHEBI:51502 , |
| NSC34391 , |
| 1,1'-diethylquino-(4)-carbocyanine iodide |
| cryptocyanine o.a. 2 |
| nk 5 |
| cryptocyanine iodide |
| kryptocyanine iodide |
| nsc-34391 |
| 1,4'-carbocyanine iodide |
| eastman 1334 |
| kryptocyanine |
| kryptocyanin |
| 1,4'-quinocarbocyanine iodide |
| nk 5 (dye) |
| CHEMBL1989021 |
Roles (1)
| Role | Description |
|---|
| fluorochrome | A fluorescent dye used to stain biological specimens. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (2)
| Class | Description |
|---|
| quinolines | A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring. |
| organic iodide salt | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID658163 | Stabilization of DNA duplex hairpin structure assessed as change in melting temperature at 1 uM by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. |
| AID658162 | Stabilization of human G-quadruplex F21T assessed as change in melting temperature at 1 uM by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. |
| AID658164 | Stabilization of human G-quadruplex F21T assessed as change in melting temperature at 5 uM by FRET assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8
| Identification of novel telomeric G-quadruplex-targeting chemical scaffolds through screening of three NCI libraries. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 47.64
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 47.64 (24.57) | | Research Supply Index | 1.95 (2.92) | | Research Growth Index | 4.99 (4.65) | | Search Engine Demand Index | 69.20 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (16.67%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (83.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |