Page last updated: 2024-09-04

n(3)-ethylthymidine and thymidine

n(3)-ethylthymidine has been researched along with thymidine in 6 studies

*Thymidine: A nucleoside in which THYMINE is linked to DEOXYRIBOSE. [MeSH]

*Thymidine: A nucleoside in which THYMINE is linked to DEOXYRIBOSE. [MeSH]

Compound Research Comparison

Studies
(n(3)-ethylthymidine)
Trials
(n(3)-ethylthymidine)
Recent Studies (post-2010)
(n(3)-ethylthymidine)
Studies
(thymidine)
Trials
(thymidine)
Recent Studies (post-2010) (thymidine)
80433,4102411,117

Protein Interaction Comparison

ProteinTaxonomyn(3)-ethylthymidine (IC50)thymidine (IC50)
Thymidine kinase Macacine alphaherpesvirus 14.1
Thymidine kinase, cytosolicHomo sapiens (human)0.614
Thymidine kinaseHuman alphaherpesvirus 1 strain SC161
Sterol O-acyltransferase 1Cricetulus griseus (Chinese hamster)1.8

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhanot, OS; Donahue, JM; Grevatt, PC1
Bhanot, OS; Donahue, JM; Gabrielides, CN; Grevatt, PC; Solomon, JJ1
Chen, HJ; Lee, CR1
Wang, P; Wang, Y; Zhai, Q1
Dai, X; Wang, P; Wang, Y; You, C1
Dai, X; Nay, SL; O'Connor, TR; Wang, J; Wang, P; Wang, Y; You, C1

Other Studies

6 other study(ies) available for n(3)-ethylthymidine and thymidine

ArticleYear
The role of N3-ethyldeoxythymidine in mutagenesis and cytotoxicity by ethylating agents.
    The Journal of biological chemistry, 1991, Jan-15, Volume: 266, Issue:2

    Topics: Alkylating Agents; Animals; Base Sequence; Cell Survival; DNA Replication; Manganese Poisoning; Molecular Sequence Data; Mutagenesis; Polymerase Chain Reaction; Rats; Templates, Genetic; Thymidine; Tumor Cells, Cultured

1991
Incorporation of dA opposite N3-ethylthymidine terminates in vitro DNA synthesis.
    Biochemistry, 1990, Nov-13, Volume: 29, Issue:45

    Topics: Bacteriophage phi X 174; Base Composition; Base Sequence; Deoxyadenine Nucleotides; DNA; Ethylnitrosourea; Hydrogen Bonding; Molecular Sequence Data; Mutation; Templates, Genetic; Thymidine

1990
Detection and simultaneous quantification of three smoking-related ethylthymidine adducts in human salivary DNA by liquid chromatography tandem mass spectrometry.
    Toxicology letters, 2014, Jan-03, Volume: 224, Issue:1

    Topics: Adult; Chromatography, Liquid; DNA Adducts; Humans; Male; Saliva; Smoking; Tandem Mass Spectrometry; Thymidine

2014
Cytotoxic and mutagenic properties of regioisomeric O²-, N3- and O⁴-ethylthymidines in bacterial cells.
    Carcinogenesis, 2014, Volume: 35, Issue:9

    Topics: Base Sequence; DNA Damage; DNA Mutational Analysis; DNA Replication; DNA, Bacterial; Escherichia coli; Mutagens; Mutation Rate; Thymidine

2014
Transcriptional bypass of regioisomeric ethylated thymidine lesions by T7 RNA polymerase and human RNA polymerase II.
    Nucleic acids research, 2014, Dec-16, Volume: 42, Issue:22

    Topics: Cell Line; DNA Damage; DNA-Directed RNA Polymerases; HEK293 Cells; HeLa Cells; Humans; RNA Polymerase II; Thymidine; Transcription, Genetic; Viral Proteins

2014
Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions.
    ACS chemical biology, 2016, 05-20, Volume: 11, Issue:5

    Topics: AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; AlkB Homolog 3, Alpha-Ketoglutarate-Dependent Dioxygenase; Alkylation; Animals; Cell Line; DNA Adducts; DNA Glycosylases; DNA Repair; Humans; Mice; Thymidine

2016