Compounds > libexin
Page last updated: 2024-11-07

libexin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

libexin: RN given refers to mono-HCl; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID120507
SCHEMBL ID1609874
MeSH IDM0051987

Synonyms (31)

Synonym
libexin (tn)
1-(2-(3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl)ethyl)piperidine,monohydrochloride
3-(2,2-diphenylaethyl)-5-(2-piperidinoaethyl)-1,2,4-oxadiazol [german]
libexin
einecs 213-567-6
tibexin
prenoxdiazine hydrochloride
hk 256
piperidine, 1-(2-(3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl)ethyl)-, monohydrochloride
lomapect
1-(2-(3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl)ethyl)piperidine monohydrochloride
982-43-4
D08417
3-(2,2-diphenylaethyl)-5-(2-piperidinoaethyl)-1,2,4-oxadiazol
390ww7v7mz ,
unii-390ww7v7mz
toparten
prenoxdiazine hydrochloride [mi]
hk-256
libeksin
piperidine, 1-(2-(3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl)ethyl)-, hydrochloride (1:1)
prenoxdiazin hydrochloride [who-dd]
prenoxdiazin hydrochloride
SCHEMBL1609874
DTXSID00243511
AKOS027378749
lomapect;hk 256;prenoxdiazine
3-(2,2-diphenylethyl)-5-(2-(piperidin-1-yl)ethyl)-1,2,4-oxadiazole hydrochloride
3-(2,2-diphenylethyl)-5-(2-piperidin-1-ylethyl)-1,2,4-oxadiazole;hydrochloride
Q27256838
1-[2-[3-(2,2-diphenylethyl)-1,2,4-oxadiazol-5-yl]ethyl]piperidine,monohydrochloride
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 64.69

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index64.69 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index104.33 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (64.69)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (20.00%)5.53%
Reviews1 (10.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (70.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
diphenhydramine hydrochloride
Antitussive Agents: Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.. diphenhydramine hydrochloride : The hydrochloride salt of diphenhydramine.		5.5451hydrochloride;
organoammonium salt		anti-allergic agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
sedative
emetine
Emetine: The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.. emetine : A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.		6.9510isoquinoline alkaloid;
pyridoisoquinoline		antiamoebic agent;
anticoronaviral agent;
antiinfective agent;
antimalarial;
antineoplastic agent;
antiprotozoal drug;
antiviral agent;
autophagy inhibitor;
emetic;
expectorant;
plant metabolite;
protein synthesis inhibitor
codeine
[no description available]		3.3311morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic
oxadiazoles
Oxadiazoles: Compounds containing five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom which exist in various regioisomeric forms.		4.4451
piperidines
Piperidines: A family of hexahydropyridines.		6.0591
ConditionIndicatedRelationship StrengthStudiesTrials
Bacterial Disease
[description not available]		02.0310
Complications, Pregnancy
[description not available]		02.0310
Abnormalities, Drug-Induced
Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.		02.0310
Bacterial Infections
Infections by bacteria, general or unspecified.		02.0310
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		02.0310
Disease, Pulmonary
[description not available]		01.9610
Cough
A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.		04.0331
Lung Diseases
Pathological processes involving any part of the LUNG.		01.9610
Chronic Illness
[description not available]		03.7421
Chronic Disease
Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).		03.7421
Respiratory Tract Diseases
Diseases involving the RESPIRATORY SYSTEM.		08.2820
Acute Disease
Disease having a short and relatively severe course.		03.3311