Page last updated: 2024-11-08

lf 150195

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

LF 150195: an immunosuppressive agent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID179332
CHEMBL ID357764
SCHEMBL ID8778920
MeSH IDM0397549

Synonyms (19)

Synonym
lf 150195
anisperimus
CHEMBL357764
[2-[6-(diaminomethylideneamino)hexylamino]-2-oxoethyl] n-[4-[[(3r)-3-aminobutyl]amino]butyl]carbamate
170368-04-4
d0514p112g ,
((6-guanidinohexyl)carbamomoyl)methyl(4-(((r)-3-aminobutyl)amino)butyl)carbamate
anisperimus [inn]
unii-d0514p112g
lf-15-0195
lf 15-0195
lf150195
lf-150195
SCHEMBL8778920
DTXSID10168847
6-(diaminomethylideneamino)hexylcarbamoylmethyl n-[4-[[(3r)-3-aminobutyl]amino]butyl]carbamate
Q27275922
2-((6-guanidinohexyl)amino)-2-oxoethyl (r)-(4-((3-aminobutyl)amino)butyl)carbamate
AKOS040750524
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID134270Tested in vivo against mouse graft-versus-host disease(GVHD) for survival (mean) after daily administration of 0.3 mg/kg (i.p.) using group of 8 mice/dose for 10 days.1999Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
AID134271Tested in vivo against mouse graft-versus-host disease(GVHD) for survival (mean) after daily administration of 3 mg/kg (i.p.) using group of 8 mice/dose for 10 days.1999Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
AID186900The compound was tested in vivo against heart transplanted rat for survival (mean) after daily administration of 2.5 mg/kg(ip) for 10 days.1999Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (31)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's29 (93.55)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index3.50 (2.92)
Research Growth Index6.21 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other32 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]