Page last updated: 2024-12-08
lf 150195
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
LF 150195: an immunosuppressive agent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
---|---|
PubMed CID | 179332 |
CHEMBL ID | 357764 |
SCHEMBL ID | 8778920 |
MeSH ID | M0397549 |
Synonyms (19)
Synonym |
---|
lf 150195 |
anisperimus |
CHEMBL357764 |
[2-[6-(diaminomethylideneamino)hexylamino]-2-oxoethyl] n-[4-[[(3r)-3-aminobutyl]amino]butyl]carbamate |
170368-04-4 |
d0514p112g , |
((6-guanidinohexyl)carbamomoyl)methyl(4-(((r)-3-aminobutyl)amino)butyl)carbamate |
anisperimus [inn] |
unii-d0514p112g |
lf-15-0195 |
lf 15-0195 |
lf150195 |
lf-150195 |
SCHEMBL8778920 |
DTXSID10168847 |
6-(diaminomethylideneamino)hexylcarbamoylmethyl n-[4-[[(3r)-3-aminobutyl]amino]butyl]carbamate |
Q27275922 |
2-((6-guanidinohexyl)amino)-2-oxoethyl (r)-(4-((3-aminobutyl)amino)butyl)carbamate |
AKOS040750524 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID134270 | Tested in vivo against mouse graft-versus-host disease(GVHD) for survival (mean) after daily administration of 0.3 mg/kg (i.p.) using group of 8 mice/dose for 10 days. | 1999 | Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23 | Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety. |
AID134271 | Tested in vivo against mouse graft-versus-host disease(GVHD) for survival (mean) after daily administration of 3 mg/kg (i.p.) using group of 8 mice/dose for 10 days. | 1999 | Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23 | Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety. |
AID186900 | The compound was tested in vivo against heart transplanted rat for survival (mean) after daily administration of 2.5 mg/kg(ip) for 10 days. | 1999 | Journal of medicinal chemistry, Nov-18, Volume: 42, Issue:23 | Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (31)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (3.23) | 18.2507 |
2000's | 29 (93.55) | 29.6817 |
2010's | 1 (3.23) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.72
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.72) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 32 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |