lf 150195 has been researched along with Graft vs Host Disease in 2 studies
*Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Annat, J; Carboni, B; Dutartre, P; Jost, E; Lebreton, L; Renaut, P; Vaultier, M | 1 |
| de Fornel, D; Dubrez-Daloz, L; Ducoroy, P; Dutartre, P; Micheau, O; Perruche, S; Saas, P; Solary, E | 1 |
2 other study(ies) available for lf 150195 and Graft vs Host Disease
| Article | Year |
|---|---|
Structure-immunosuppressive activity relationships of new analogues of 15-deoxyspergualin. 2. Structural modifications of the spermidine moiety.
Topics: Animals; Carbamates; Drug Evaluation, Preclinical; Graft vs Host Disease; Guanidines; Heart Transplantation; Immunosuppressive Agents; Mice; Rats; Rats, Inbred Lew; Spermidine; Stereoisomerism; Structure-Activity Relationship; Transplantation, Homologous | 1999 |
LF 15-0195 immunosuppressive agent enhances activation-induced T-cell death by facilitating caspase-8 and caspase-10 activation at the DISC level.
Topics: Animals; Blood Cells; Bone Marrow Transplantation; Caspase 10; Caspase 8; Caspase 9; Caspases; Cell Death; Death Domain Receptor Signaling Adaptor Proteins; fas Receptor; Graft vs Host Disease; Guanidines; Humans; Immunosuppressive Agents; Jurkat Cells; Lymphocyte Activation; Mice; Models, Animal; Receptors, Tumor Necrosis Factor; T-Lymphocytes | 2003 |