lf 150195 has been researched along with sirolimus in 2 studies
| Studies (lf 150195) | Trials (lf 150195) | Recent Studies (post-2010) (lf 150195) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
|---|---|---|---|---|---|
| 32 | 0 | 1 | 20,711 | 2,368 | 11,516 |
| Protein | Taxonomy | lf 150195 (IC50) | sirolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dutartre, P; Garcia, B; Jevnikar, AM; Min, W; O'Brien, C; Shum, J; Zhong, R; Zhou, D | 1 |
| Garcia, B; Jiang, J; Liu, Y; Ross, DC; Sun, H; Temple, CL; Wang, H; Zhong, R; Zhong, T | 1 |
2 other study(ies) available for lf 150195 and sirolimus
| Article | Year |
|---|---|
LF 15-0195, a novel immunosuppressive agent prevents rejection and induces operational tolerance in a mouse cardiac allograft model.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Sirolimus; Transplantation Tolerance; Transplantation, Homologous | 2003 |
Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, and rapamycin in a mouse model.
Topics: Animals; Antibodies, Monoclonal; Extremities; Graft Survival; Guanidines; Immunosuppressive Agents; Isoantibodies; Leukocyte Common Antigens; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Models, Animal; Sirolimus; Skin Transplantation; Transplantation Chimera; Transplantation, Homologous | 2007 |