dehydroglyasperin C: isolated from licorice, caused Nrf2-mediated induction of detoxifying enzymes; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
---|---|
PubMed CID | 480775 |
SCHEMBL ID | 5614039 |
MeSH ID | M0545583 |
Synonym |
---|
4-[7-hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-2h-1-benzopyran-3-yl]-benzene-1,3-diol |
dehydroglyasperin c |
4-[7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-2h-chromen-3-yl]benzene-1,3-diol |
SCHEMBL5614039 |
unii-80h8msz44i |
1,3-benzenediol, 4-(7-hydroxy-5-methoxy-6-(3-methyl-2-butenyl)-2h-1-benzopyran-3-yl)- |
80H8MSZ44I , |
1,3-benzenediol, 4-(7-hydroxy-5-methoxy-6-(3-methyl-2-buten-1-yl)-2h-1-benzopyran-3-yl)- |
199331-35-6 |
AKOS032949120 |
dehydroglyasperinc |
Q27269145 |
MS-25524 |
E80707 |
CS-0113425 |
HY-N7335 |
Dehydroglyasperin C (DGC) is a major isoflavone found in the root of licorice.
Excerpt | Reference | Relevance |
---|---|---|
"Dehydroglyasperin C (DGC) is a major isoflavone found in the root of licorice." | ( Dehydroglyasperin C suppresses TPA-induced cell transformation through direct inhibition of MKK4 and PI3K. Heo, YS; Jang, YJ; Jung, SK; Kim, JE; Kim, JR; Lee, CC; Lee, CY; Lee, E; Lee, HJ; Lee, JH; Lee, KW; Lim, SS; Lim, TG; Seo, SG; Son, JE, 2016) | 2.6 |
Excerpt | Reference | Relevance |
---|---|---|
"Dehydroglyasperin C treatment also decreased the UVB irradiation-mediated activation of mitogen-activated protein kinase (MAPK), c-Jun phosphorylation, and c-Fos expression." | ( The effect of dehydroglyasperin C on UVB-mediated MMPs expression in human HaCaT cells. Ha, JH; Jeong, YJ; Park, SN; Park, YM; Xuan, SH, 2017) | 1.54 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 9 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (17.88) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 9 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |