cyclobut A: structure given in first source; RN given refers to the (1alpha,2beta,3alpha)-(+-)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 122100 |
| CHEMBL ID | 30657 |
| SCHEMBL ID | 1980695 |
| MeSH ID | M0172631 |
| Synonym |
|---|
| c-oxt-a |
| 124770-85-0 |
| carboxetanocin a |
| CHEMBL30657 |
| [3-(6-aminopurin-9-yl)-2-(hydroxymethyl)cyclobutyl]methanol |
| 9-(2,3-bis(hydroxymethyl)-1-cyclobutyl)adenine |
| carbocyclic oxetanocin a |
| cyclobut a |
| 1,2-cyclobutanedimethanol, 3-(6-amino-9h-purin-9-yl)-, (1alpha,2beta,3alpha)-(+-)- |
| cyclobut-a |
| SCHEMBL1980695 |
| 9-(2',3'-bis(hydroxymethyl)cyclobutyl)adenine |
| PYJIWOQTJHPDAK-UHFFFAOYSA-N |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID104097 | compound was tested for antiherpes activity against MCMV(Smith) in tissue culture by plaque reduction assay | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues. |
| AID85277 | compound was tested for antiherpes activity against HSV-2(186) in tissue culture by plaque reduction assay | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues. |
| AID80127 | compound was tested for antiherpes activity against HCMV(AD 169) in tissue culture by plaque reduction assay | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues. |
| AID217678 | compound was tested for antiherpes activity against VZV(Ellen) in tissue culture by plaque reduction assay | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues. |
| AID84405 | compound was tested for antiherpes activity against HSV-1(Schooler) in tissue culture by plaque reduction assay | 1991 | Journal of medicinal chemistry, Apr, Volume: 34, Issue:4 | Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.01) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||