Page last updated: 2024-12-08
borreverine
Description
borreverine: extract from Borreria verticillata; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
Synonyms (10)
| Synonym |
|---|
| 51109-65-0 |
| borreverine |
| C09082 , |
| AC1L9C4E , |
| CHEBI:3156 |
| n-methyl-2-[2-[(1s,9r,10s,15r,16r)-12,14,14,19-tetramethyl-8,19-diazapentacyclo[7.7.3.01,9.02,7.010,15]nonadeca-2,4,6,11-tetraen-16-yl]-1h-indol-3-yl]ethanamine |
| Q27105960 |
| n-methyl-2-{2-[1,1,3,13-tetramethyl-2,4a,10,10a-tetrahydro-1h,5h-4b,9b-(epiminoethano)indeno[1,2-b]indol-10-yl]-1h-indol-3-yl}ethan-1-amine |
| DTXSID60965388 |
| CHEMBL4163038 |
Drug Classes (1)
| Class | Description |
|---|
| pyrroloindole | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1504883 | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 after 72 hrs by DAPI staining based confocal microplate imaging method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. |
| AID1504889 | Selectivity index, ratio of IC50 for HEK293 cells to IC50 for chloroquine-sensitive Plasmodium falciparum 3D7 | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. |
| AID1504885 | Cytotoxicity against HEK293 cells after 72 hrs by resazurin dye based assay | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. |
| AID1504881 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum Dd2 after 72 hrs by DAPI staining based confocal microplate imaging method | 2017 | Journal of natural products, 12-22, Volume: 80, Issue:12
| Pimentelamines A-C, Indole Alkaloids Isolated from the Leaves of the Australian Tree Flindersia pimenteliana. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |