Page last updated: 2024-12-08

bisdechlorogeodin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bisdechlorogeodin: a fungus-derived nucleoside transport inhibitor; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID168966
CHEMBL ID512514
CHEBI ID22899
MeSH IDM0107702

Synonyms (15)

Synonym
CHEBI:22899 ,
bisdechlorogeodin
3209-31-2
methyl 4-hydroxy-6-methyl-4'-oxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate
bis-dechlorogeodin
4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-spiro(benzofuran-2(3h),1'-(2,5)cyclohexadiene)-2'-carboxylic acid methyl ester
spiro(benzofuran-2(3h),1'-(2,5)cyclohexadiene)-2'-carboxylic acid, 4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-, methyl ester
CHEMBL512514
methyl 4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate
c3368-a
antibiotic c3368-a
AKOS030213174
Q27109574
methyl 4-hydroxy-6'-methoxy-6-methyl-3,4'-dioxo-3h-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate
DTXSID00953966
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
antimicrobial agentA substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
oxaspiro compoundA spiro compound in which at least one of the cyclic components is an oxygen heterocyle.
1-benzofuransA member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof.
methyl esterAny carboxylic ester resulting from the formal condensation of a carboxy group with methanol.
cyclohexadiene
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (4)

Assay IDTitleYearJournalArticle
AID338306Antimicrobial activity against Escherichia coli at <200 ppm2002Journal of natural products, Jan, Volume: 65, Issue:1
New chlorinated diphenyl ethers from an Aspergillus species.
AID338307Antimicrobial activity against Gaeumannomyces graminis var. tritici at <200 ppm2002Journal of natural products, Jan, Volume: 65, Issue:1
New chlorinated diphenyl ethers from an Aspergillus species.
AID338309Antinematodal activity against Caenorhabditis elegans after 16 to 24 hrs2002Journal of natural products, Jan, Volume: 65, Issue:1
New chlorinated diphenyl ethers from an Aspergillus species.
AID338308Antimicrobial activity against Rhizoctonia solani at <200 ppm2002Journal of natural products, Jan, Volume: 65, Issue:1
New chlorinated diphenyl ethers from an Aspergillus species.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]