Page last updated: 2024-12-07
als 8123
Description
ALS 8123: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoic acid : A carboxylic acid that is 3-phenylpropanoic acid substituted at position 4 by a 2-hydroxy-3-(propan-2-ylamino)propoxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 133620 |
| CHEMBL ID | 767 |
| CHEBI ID | 143310 |
| SCHEMBL ID | 9354060 |
| MeSH ID | M0156424 |
Synonyms (27)
| Synonym |
|---|
| benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)- |
| g0sm48n856 , |
| unii-g0sm48n856 |
| als 8123 |
| CHEMBL767 , |
| CHEBI:143310 , |
| 3-{4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}propionic acid |
| 81148-15-4 |
| 3-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}propanoic acid |
| 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoic acid |
| als-8123 |
| bdbm50404792 |
| asl-8123 |
| esmolol acid |
| 3-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propionic acid |
| esmolol hydrochloride impurity, esmolol free acida- [usp impurity] |
| (+/-)-esmolol acid |
| esmolol free acid [usp impurity] |
| (r)-esmolol acid |
| benzenepropanoic acid,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]- |
| SCHEMBL9354060 |
| 3-[4-[2-hydroxy-3-(isopropylamino)propoxyl] phenyl]propionic acid |
| FT-0667972 |
| Q27225688 |
| 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoic acid |
| DTXSID801001809 |
| esmolol acid (hydrochloride) |
Research Excerpts
Pharmacokinetics
Drug Classes (3)
| Class | Description |
|---|
| carboxylic acid | A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. |
| ethanolamines | |
| secondary amino compound | A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein Targets (1)
Activation Measurements
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.38
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 12.38 (24.57) | | Research Supply Index | 1.79 (2.92) | | Research Growth Index | 4.18 (4.65) | | Search Engine Demand Index | 0.00 (26.88) | | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |