Compounds > 4-nitrophenyl-alpha-l-fucoside
Page last updated: 2024-11-06

4-nitrophenyl-alpha-l-fucoside

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

4-nitrophenylfucoside: RN given refers to (alpha-L-isomer) [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

4-nitrophenyl alpha-L-fucoside : An alpha-L-fucoside that is alpha-L-fucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID82473
CHEMBL ID4877910
CHEBI ID90253
SCHEMBL ID2288830
MeSH IDM0062414

Synonyms (37)

Synonym
4-nitrophenylfucoside
4-nitrophenyl-alpha-l-fucopyranoside
4-nitrophenyl alpha-l-fucopyranoside
10231-84-2
N0392
(2s,3s,4r,5s,6s)-2-methyl-6-(4-nitrophenoxy)oxane-3,4,5-triol
p-nitrophenyl 6-deoxy-alpha-l-galactopyranoside
einecs 233-553-3
alpha-l-galactopyranoside, 4-nitrophenyl 6-deoxy-
AKOS016011159
AKOS015897089
a-l-galactopyranoside,4-nitrophenyl 6-deoxy-
(2s,3s,4r,5s,6s)-2-methyl-6-(4-nitrophenoxy)tetrahydropyran-3,4,5-triol
SCHEMBL2288830
4-nitrophenyl a-l-fucopyranoside
(2s,3s,4r,5s,6s)-2-methyl-6-(4-nitrophenoxy)tetrahydro-2h-pyran-3,4,5-triol
4-nitrophenyl alpha-l-fucoside
4-nitrophenyl 6-deoxy-alpha-l-galactopyranoside
p-nitrophenyl alpha-l-fucoside
CHEBI:90253
4-nitrophenyl i+/--l-fucopyranoside
mfcd00063697
AS-66582
pnpalphafucp
p-nitrophenyl-alpha-l-fucoside
4-nitrophenyl-alpha-l-fucoside
pnp-alpha-l-fucopyranoside
p-nitrophenyl alpha-l-fucopyranoside
Q27162429
4-nitrophenyl alpha-l-fuco-pyran-oside
AMY41686
C14016
A896824
p-nitrophenyl ?-l-fucopyranoside
4-nitrophenyl alpha -l-fucopyranoside
DTXSID801311214
CHEMBL4877910
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
chromogenic compoundColourless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into coloured compounds. They are used in biochemical assays and in diagnosis as indicators, particularly in the form of enzyme substrates.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
alpha-L-fucoside
C-nitro compoundA nitro compound having the nitro group (-NO2) attached to a carbon atom.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1765457Substrate activity at recombinant His-tagged Bacteroides fragilis alpha L-fucosidase expressed in Escherichia coli BL21(DE3) assessed as formation of p-nitrophenyl products at 5 mM measured by UV spectrometer assay2021Bioorganic & medicinal chemistry, 07-15, Volume: 42Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates.
AID1765456Substrate activity at recombinant His-tagged Lactobacillus casei alpha L-fucosidase expressed in Escherichia coli BL(DE3) assessed as formation of p-nitrophenyl products at 5 mM measured by UV spectrometer assay2021Bioorganic & medicinal chemistry, 07-15, Volume: 42Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates.
AID1765458Substrate activity at recombinant N-terminal GFP tagged human alpha L-fucosidase expressed in HEK293T cells assessed as formation of p-nitrophenyl products at 5 mM measured by UV spectrometer assay2021Bioorganic & medicinal chemistry, 07-15, Volume: 42Comparative studies on the substrate specificity and defucosylation activity of three α-l-fucosidases using synthetic fucosylated glycopeptides and glycoproteins as substrates.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (8.33)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.48

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.48 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index5.11 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.48)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
aspartic acid
Aspartic Acid: One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.. aspartic acid : An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent. L-aspartic acid : The L-enantiomer of aspartic acid.		2.0110aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
lactose
Lactose: A disaccharide of GLUCOSE and GALACTOSE in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.. lactose : A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form.. beta-lactose : The beta-anomer of lactose.		2.2510lactose
fucose
Fucose: A six-member ring deoxysugar with the chemical formula C6H12O5. It lacks a hydroxyl group on the carbon at position 6 of the molecule.. L-fucopyranose : The pyranose form of L-fucose.. fucose : Any deoxygalactose that is deoxygenated at the 6-position.		2.3820fucopyranose;
L-fucose		Escherichia coli metabolite;
mouse metabolite
acetylglucosamine
Acetylglucosamine: The N-acetyl derivative of glucosamine.. N-acetyl-beta-D-glucosamine : An N-acetyl-D-glucosamine having beta-configuration at the anomeric centre.		1.9810N-acetyl-D-glucosamineepitope
sodium azide
Sodium Azide: A cytochrome oxidase inhibitor which is a nitridizing agent and an inhibitor of terminal oxidation. (From Merck Index, 12th ed). sodium azide : The sodium salt of hydrogen azide (hydrazoic acid).		2.0110inorganic sodium saltantibacterial agent;
explosive;
mitochondrial respiratory-chain inhibitor;
mutagen
glucose, (beta-d)-isomer
beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.		2.0510D-glucopyranoseepitope;
mouse metabolite
4-nitrophenylgalactoside
4-nitrophenylgalactoside: RN refers to (beta-D)-isomer. 4-nitrophenyl-beta-D-galactoside : A beta-D-galactopyranoside having a 4-nitrophenyl substituent at the anomeric position.		2.0310beta-D-galactoside;
monosaccharide derivative		affinity label
neocuproine
neocuproine: Spectrophotometric determination of copper and ultramicro blood sugar determinations; structure; RN given refers to parent cpd. neocuproine : A member of the class of phenanthrolines that is 1,10-phenanthroline bearing two methyl substituents at positions 2 and 9.		1.9710phenanthrolineschelator;
copper chelator
1,7-phenanthroline
[no description available]		1.9710phenanthroline
fagomine
fagomine: structure in first source		2.0510piperidines
4-nitrophenyl alpha-glucoside
4-nitrophenyl alpha-glucoside: RN given refers to (alpha)-anomer; see also (beta)-anomers: 29857-05-4, 2492-87-7; cpd with unspecified anomer: 5779-46-4. 4-nitrophenyl alpha-D-glucoside : An alpha-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.		2.0510alpha-D-glucoside;
C-nitro compound;
monosaccharide derivative		chromogenic compound
nitrophenylgalactosides
Nitrophenylgalactosides: Includes ortho-, meta-, and para-nitrophenylgalactosides.. 2-nitrophenyl beta-D-galactoside : A beta-D-galactoside having a 2-nitrophenyl substituent at the anomeric position.		2.0310beta-D-galactoside;
C-nitro compound		chromogenic compound
3'-fucosyllactose
3'-fucosyllactose: antiserum against fuc alpha 1-3 gal linkage reacted with human colon adenocarcinoma cells		2.2510
glycosides
[no description available]		3.82110
isopropyl thiogalactoside
Isopropyl Thiogalactoside: A non-metabolizable galactose analog that induces expression of the LAC OPERON.. isopropyl beta-D-thiogalactopyranoside : An S-glycosyl compound consisting of beta-D-1-thiogalactose having an isopropyl group attached to the anomeric sulfur.		2.0310S-glycosyl compound
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		1.9710organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials