2-methyl-1,2,3,4-tetrahydroquinoline: found in brains of Parkinson patients [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 96289 |
| CHEMBL ID | 589607 |
| SCHEMBL ID | 424121 |
| SCHEMBL ID | 8771344 |
| MeSH ID | M0148630 |
| Synonym |
|---|
| HMS1577N05 |
| AC-19074 |
| 2-methyl-1,2,3,4-tetrahydro-quinoline |
| NCIOPEN2_000109 |
| 2-methyl-1,3,4-tetrahydroquinoline |
| nsc-65607 |
| 1,3,4-tetrahydro-2-methylquinoline |
| 1,3,4-tetrahydroquinaldine |
| quinoline,2,3,4-tetrahydro-2-methyl- |
| quinaldine,2,3,4-tetrahydro- |
| 1780-19-4 |
| nsc65607 |
| 1,3,4-tetahydro-2-methylquinoline |
| quinoline, 1,2,3,4-tetrahydro-2-methyl- |
| quinaldine, 1,2,3,4-tetrahydro- |
| 2-methyl-1,2,3,4-tetrahydroquinoline |
| STK086402 |
| inchi=1/c10h13n/c1-8-6-7-9-4-2-3-5-10(9)11-8/h2-5,8,11h,6-7h2,1h |
| tetrahydro-2-methylquinoline |
| 25448-05-9 |
| AKOS000267397 |
| CHEMBL589607 |
| FT-0654443 |
| T0112 |
| 1,2,3,4-tetrahydroquinaldine |
| 1,2,3,4-tetrahydro-2-methylquinoline |
| EN300-59145 |
| 2-methyl-1,2,3,4-tetrahydroquinoline;1,2,3,4-tetrahydroquinaldine |
| A812332 |
| xhv42aw48x , |
| nsc 65607 |
| 1,2,3,4-tetahydro-2-methylquinoline |
| unii-xhv42aw48x |
| einecs 217-226-2 |
| ai3-15932 |
| quinoline, tetrahydro-2-methyl- |
| einecs 246-996-2 |
| (1)-1,2,3,4-tetrahydro-2-methylquinoline |
| 74497-74-8 |
| einecs 277-887-8 |
| AM84625 |
| SCHEMBL424121 |
| AKOS016039021 |
| tetrahydrochinaldin |
| SCHEMBL8771344 |
| 2-(r,s)-methyl-1,2,3,4-tetrahydro-quinoline |
| tetrahydroquinaldine |
| CS-W019554 |
| DTXSID50397311 |
| FT-0696378 |
| mfcd00023886 |
| (r)-1,2,3,4-tetrahydro-2-methylquinoline |
| 1.2.3.4-tetrahydro- quinaldine |
| SY045570 |
| DS-12521 |
| AC1627 |
| 2-methyltetrahydroquinoline |
| 5,6,7,8-tetra-quinaldine |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID456265 | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456262 | Antiplasmodial activity against chloroquine and pyrimethamine-resistant Plasmodium falciparum K1 infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456263 | Cytotoxicity against rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456261 | Antileishmanial activity against Leishmania donovani infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456259 | Antitrypanosomal activity against Trypanosoma brucei rhodesiense infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456260 | Antitrypanosomal activity against Trypanosoma cruzi infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID456264 | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma cruzi infected in rat L6 cells | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Synthesis, stereoelectronic characterization and antiparasitic activity of new 1-benzenesulfonyl-2-methyl-1,2,3,4-tetrahydroquinolines. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.30) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||