Page last updated: 2024-12-06
2,5-bis(hydroxymethyl)furan
Description
2,5-bis(hydroxymethyl)furan, also known as 2,5-furandicarboxaldehyde, is a potential platform chemical derived from biomass. It is a colorless crystalline solid with a melting point of 118-120 °C. The compound can be synthesized through various methods, including the reduction of 2,5-furandicarboxylic acid, a readily available product from the dehydration of biomass-derived sugars. 2,5-bis(hydroxymethyl)furan holds significant potential as a building block for various polymers, resins, and pharmaceuticals. Its importance lies in its renewable origin and its ability to replace petroleum-based feedstocks. Researchers are exploring its potential applications in the synthesis of bio-based polymers, such as polyesters and polyamides. Due to its promising properties and its sustainable nature, 2,5-bis(hydroxymethyl)furan is actively studied for its potential to contribute to a more environmentally friendly and sustainable chemical industry.'
2,5-dihydroxymethylfuran: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 74663 |
| CHEMBL ID | 4303433 |
| CHEBI ID | 59984 |
| SCHEMBL ID | 183551 |
| MeSH ID | M0157760 |
Synonyms (60)
| Synonym |
|---|
| nsc-40737 |
| nsc40737 |
| 1883-75-6 |
| 2,5-furandimethanol , |
| nsc-524614 |
| nsc524614 |
| inchi=1/c6h8o3/c7-3-5-1-2-6(4-8)9-5/h1-2,7-8h,3-4h |
| furan-2,5-diyldimethanol |
| EC-000.1543 |
| nsc 40737 |
| [5-(hydroxymethyl)furan-2-yl]methanol |
| 5-(hydroxymethyl)-furfuryl alcohol |
| 2,5-bis-hydroxymethylfuran |
| 2,5-di(hydroxymethyl)furan |
| 2,5-furanylmethanol |
| 2,5-bis(hydroxymethyl)furan |
| CHEBI:59984 , |
| (furan-2,5-diyl)dimethanol |
| 5-(hydroxymethyl)furfuryl alcohol |
| 2,5-bis(hydroxymethyl)furan; 2,5-di(hydroxymethyl)furan; 5-(hydroxymethyl)-furfuryl alcohol |
| A4161 |
| AKOS006282605 |
| 2,5-dihydroxymethyl-furane |
| 5-hydroxymethylfurfuryl alcohol |
| C20443 |
| 4xe4jyn4g7 , |
| unii-4xe4jyn4g7 |
| einecs 217-544-1 |
| nsc 524614 |
| GEO-02495 |
| FT-0633892 |
| AM20090102 |
| EPITOPE ID:136041 |
| 5-(hydroxymethyl)furfurylalcohol |
| 2,5-bishydroxymethylfuran |
| (5-hydroxymethylfuran-2-yl)methanol |
| furan-2,5-dimethanol |
| 2,5-dihydroxymethylfuran |
| 2,5-bis-(hydroxymethyl)furan |
| SCHEMBL183551 |
| [5-(hydroxymethyl)-2-furyl]methanol |
| DTXSID2062036 |
| mfcd00003253 |
| SY030052 |
| 2,5-di-(hydroxymethyl)furan |
| W-200189 |
| TS-01680 |
| AC-22969 |
| 2,5-bis-(hydroxymethyl)-furane |
| CS-W018568 |
| Q4596786 |
| BCP14976 |
| CHEMBL4303433 |
| furan 2,5-dimethanol |
| SB60896 |
| HY-W017782 |
| 2,5-bis(hydroxylmethyl)furan |
| farez 6305 |
| EN300-85888 |
| PD053824 |
Drug Classes (2)
| Class | Description |
|---|
| furans | Compounds containing at least one furan ring. |
| diol | A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (15)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 7 (46.67) | 24.3611 |
| 2020's | 6 (40.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 27.51
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 27.51 (24.57) | | Research Supply Index | 2.77 (2.92) | | Research Growth Index | 5.61 (4.65) | | Search Engine Demand Index | 29.35 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 15 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |