Compounds > 1,2-difluorobenzene
Page last updated: 2024-11-05

1,2-difluorobenzene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,2-difluorobenzene : A difluorobenzene carrying fluoro groups at positions 1 and 2. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

difluorobenzene : Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID9706
CHEBI ID38583
SCHEMBL ID45406
MeSH IDM0216548

Synonyms (43)

Synonym
10-27-5
ortho-difluorobenzene
CHEBI:38583
1,2-difluorbenzol
nsc 10275
einecs 206-680-7
ai3-52226
brn 1905113
1,2-difluorobenzene
o-difluorobenzene
nsc10275
benzene,2-difluoro-
nsc-10275
367-11-3
benzene, o-difluoro-
benzene, 1,2-difluoro-
inchi=1/c6h4f2/c7-5-3-1-2-4-6(5)8/h1-4
1,2-difluorobenzene, 98%
D1627
AKOS000120159
aw7qgmw29c ,
4-05-00-00637 (beilstein handbook reference)
unii-aw7qgmw29c
A823337
1,2-bis(fluoranyl)benzene
1,2-difluoro-benzene
o-difluoro benzene
FT-0606397
AM61500
difluorobenzene
0-difluorobenzene
SCHEMBL45406
W-106597
mfcd00000284
DTXSID2075390
F0001-1048
(3r pound not4r)-3-hydroxy-3 pound not4-bis[(4-hydroxy-3-methoxy-phenyl)methyl]oxolan-2- one
BCP25286
2,3-difluoro benzene
Q425257
EN300-19236
PS-11966
Z104473256
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
anaestheticSubstance which produces loss of feeling or sensation.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
difluorobenzeneAny member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.83

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index36.83 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index5.01 (4.65)
Search Engine Demand Index45.47 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (36.83)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzene
[no description available]		2.4420aromatic annulene;
benzenes;
volatile organic compound		carcinogenic agent;
environmental contaminant;
non-polar solvent
halothane
[no description available]		2.0310haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound		inhalation anaesthetic
propofol
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.. propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.		2.0310phenolsanticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative
resorcinol
resorcinol: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7951. resorcinol : A benzenediol that is benzene dihydroxylated at positions 1 and 3.		2.0310benzenediol;
phenolic donor;
resorcinols		erythropoietin inhibitor;
sensitiser
ethylbenzene
[no description available]		2.0810alkylbenzene
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.		2.4110pyrrole;
secondary amine
hexafluorobenzene
[no description available]		2.7330fluorobenzenes;
fluorocarbon		NMR chemical shift reference compound
fluorobenzenes
Fluorobenzenes: Derivatives of BENZENE that contain FLUORINE.. monofluorobenzene : The simplest member of the class of monofluorobenzenes that is benzene carrying a single fluoro substituent.. fluorobenzenes : Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group.		3.4370monofluorobenzenesNMR chemical shift reference compound
tungsten
Tungsten: A metallic element with the atomic symbol W, atomic number 74, and atomic weight 183.85. It is used in many manufacturing applications, including increasing the hardness, toughness, and tensile strength of steel; manufacture of filaments for incandescent light bulbs; and in contact points for automotive and electrical apparatus.		7.4110chromium group element atommicronutrient
fluorides
[no description available]		2.0310halide anion;
monoatomic fluorine
ConditionIndicatedRelationship StrengthStudiesTrials
Ache
[description not available]		02.0410
Decerebrate Posturing
[description not available]		02.0410
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.		02.0410