Page last updated: 2024-12-06
1,2,4,5-tetrahydroxybenzene
Description
1,2,4,5-tetrahydroxybenzene is a chemical compound also known as **tetrahydroxybenzene** or **THB**. It is a colorless, crystalline solid that is highly soluble in water.
**Structure:**
As the name suggests, THB is a benzene ring with four hydroxyl (-OH) groups attached to it at positions 1, 2, 4, and 5.
**Importance in Research:**
THB is a versatile compound that has several important applications in research, particularly in the fields of:
* **Organic Chemistry:** THB is a valuable building block for the synthesis of various organic compounds, including pharmaceuticals, dyes, and polymers. Its high reactivity and multiple hydroxyl groups make it a useful starting material for various reactions.
* **Medicinal Chemistry:** THB and its derivatives have shown promising biological activity, particularly as antioxidants, anti-inflammatory agents, and potential anticancer drugs.
* **Antioxidant Properties:** THB can scavenge free radicals, which can damage cells and contribute to disease development.
* **Anti-inflammatory Properties:** THB can inhibit the production of inflammatory mediators, which play a role in chronic diseases like arthritis and cancer.
* **Materials Science:** THB can be used to create new materials with unique properties, such as polymers with high conductivity or improved mechanical strength.
* **Environmental Science:** THB and its derivatives can be used in the development of environmental remediation technologies, such as the removal of heavy metals from wastewater.
**Research Focus:**
Current research on THB focuses on:
* **Synthesis and Characterization:** Developing efficient methods for the synthesis of THB and its derivatives with desired properties.
* **Biological Activity Studies:** Investigating the mechanisms of action of THB and its derivatives in different biological systems.
* **Drug Development:** Identifying and developing potential therapeutic applications of THB and its derivatives.
* **Materials Development:** Exploring the use of THB in the creation of novel materials with enhanced properties.
**Conclusion:**
1,2,4,5-tetrahydroxybenzene is a valuable compound with significant potential in various research areas. Its unique structure and versatile properties make it a promising molecule for the development of new drugs, materials, and environmental technologies.
1,2,4,5-tetrahydroxybenzene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 69464 |
SCHEMBL ID | 67178 |
MeSH ID | M0397748 |
Synonyms (25)
Synonym |
nsc144257 |
nsc-144257 |
1,4,5-benzenetetrol |
636-32-8 |
benzene-1,2,4,5-tetrol |
1,2,4,5-benzenetetrol |
nsc 144257 |
unii-lr3fb2ftn2 |
lr3fb2ftn2 , |
1wg , |
benzene-1,2,4,5-tetraol , |
SCHEMBL67178 |
AKOS022633995 |
UYQMSQMCIYSXOW-UHFFFAOYSA-N |
1,2,4,5-tetrahydroxybenzene |
DTXSID10212975 |
Q27458545 |
CS-16307 |
mfcd19441381 |
CS-0095053 |
C75984 |
A868084 |
YSZC084 |
SY277076 |
2,5-dihydroxyhydroquinone |
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 2 (33.33) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (50.00) | 29.6817 |
2010's | 1 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 19.78
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 19.78 (24.57) | Research Supply Index | 1.95 (2.92) | Research Growth Index | 4.09 (4.65) | Search Engine Demand Index | 15.26 (26.88) | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (16.67%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (83.33%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |