Page last updated: 2024-12-06

1,2,4,5-tetrahydroxybenzene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,2,4,5-tetrahydroxybenzene is a chemical compound also known as **tetrahydroxybenzene** or **THB**. It is a colorless, crystalline solid that is highly soluble in water.

**Structure:**

As the name suggests, THB is a benzene ring with four hydroxyl (-OH) groups attached to it at positions 1, 2, 4, and 5.

**Importance in Research:**

THB is a versatile compound that has several important applications in research, particularly in the fields of:

* **Organic Chemistry:** THB is a valuable building block for the synthesis of various organic compounds, including pharmaceuticals, dyes, and polymers. Its high reactivity and multiple hydroxyl groups make it a useful starting material for various reactions.
* **Medicinal Chemistry:** THB and its derivatives have shown promising biological activity, particularly as antioxidants, anti-inflammatory agents, and potential anticancer drugs.
* **Antioxidant Properties:** THB can scavenge free radicals, which can damage cells and contribute to disease development.
* **Anti-inflammatory Properties:** THB can inhibit the production of inflammatory mediators, which play a role in chronic diseases like arthritis and cancer.
* **Materials Science:** THB can be used to create new materials with unique properties, such as polymers with high conductivity or improved mechanical strength.
* **Environmental Science:** THB and its derivatives can be used in the development of environmental remediation technologies, such as the removal of heavy metals from wastewater.

**Research Focus:**

Current research on THB focuses on:

* **Synthesis and Characterization:** Developing efficient methods for the synthesis of THB and its derivatives with desired properties.
* **Biological Activity Studies:** Investigating the mechanisms of action of THB and its derivatives in different biological systems.
* **Drug Development:** Identifying and developing potential therapeutic applications of THB and its derivatives.
* **Materials Development:** Exploring the use of THB in the creation of novel materials with enhanced properties.

**Conclusion:**

1,2,4,5-tetrahydroxybenzene is a valuable compound with significant potential in various research areas. Its unique structure and versatile properties make it a promising molecule for the development of new drugs, materials, and environmental technologies.

1,2,4,5-tetrahydroxybenzene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID69464
SCHEMBL ID67178
MeSH IDM0397748

Synonyms (25)

Synonym
nsc144257
nsc-144257
1,4,5-benzenetetrol
636-32-8
benzene-1,2,4,5-tetrol
1,2,4,5-benzenetetrol
nsc 144257
unii-lr3fb2ftn2
lr3fb2ftn2 ,
1wg ,
benzene-1,2,4,5-tetraol ,
SCHEMBL67178
AKOS022633995
UYQMSQMCIYSXOW-UHFFFAOYSA-N
1,2,4,5-tetrahydroxybenzene
DTXSID10212975
Q27458545
CS-16307
mfcd19441381
CS-0095053
C75984
A868084
YSZC084
SY277076
2,5-dihydroxyhydroquinone
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (33.33)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.78

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.78 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.09 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.78)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]