Page last updated: 2024-10-06

HIF-1-alpha transcription factor network

Proteins (65)

ProteinSynonymsTaxonomy
Ferrochelatase, mitochondrialEC 4.99.1.1; Heme synthase; Protoheme ferro-lyaseHomo sapiens (human)
COP9 signalosome complex subunit 5SGN5; Signalosome subunit 5; EC 3.4.-.-; Jun activation domain-binding protein 1Homo sapiens (human)
Fructose-bisphosphate aldolase AEC 4.1.2.13; Lung cancer antigen NY-LU-1; Muscle-type aldolaseHomo sapiens (human)
ATP-dependent translocase ABCB1ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; 7.6.2.2; P-glycoprotein 1; Phospholipid transporter ABCB1; 7.6.2.1Homo sapiens (human)
Pyruvate kinase PKMEC 2.7.1.40; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58Homo sapiens (human)
RAC-alpha serine/threonine-protein kinaseEC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alphaHomo sapiens (human)
Nitric oxide synthase, inducibleEC 1.14.13.39; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2Homo sapiens (human)
Nuclear receptor ROR-alphaNuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alphaHomo sapiens (human)
Induced myeloid leukemia cell differentiation protein Mcl-1Bcl-2-like protein 3; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; mcl1/EATHomo sapiens (human)
Hypoxia-inducible factor 1-alphaHIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8Homo sapiens (human)
Carbonic anhydrase 9EC 4.2.1.1; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1Homo sapiens (human)
Histone deacetylase 7HD7; EC 3.5.1.98; Histone deacetylase 7A; HD7aHomo sapiens (human)
Broad substrate specificity ATP-binding cassette transporter ABCG2EC 7.6.2.2; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporterHomo sapiens (human)
Phosphoglycerate kinase 1 EC 2.7.2.3; Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2Homo sapiens (human)
Endothelin-1Preproendothelin-1; PPET1Homo sapiens (human)
Telomerase reverse transcriptaseEC 2.7.7.49; HEST2; Telomerase catalytic subunit; Telomerase-associated protein 2; TP2Homo sapiens (human)
L-lactate dehydrogenase A chainLDH-A; EC 1.1.1.27; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59Homo sapiens (human)
SerotransferrinTransferrin; Beta-1 metal-binding globulin; SiderophilinHomo sapiens (human)
Integrin beta-2Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit betaHomo sapiens (human)
Transcription factor AP-1Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39Homo sapiens (human)
Heme oxygenase 1HO-1; EC 1.14.14.18Homo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 1Glucose transporter type 1, erythrocyte/brain; GLUT-1; HepG2 glucose transporterHomo sapiens (human)
Hexokinase-4HK4; EC 2.7.1.1; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-DHomo sapiens (human)
Hepatocyte nuclear factor 4-alphaHNF-4-alpha; Nuclear receptor subfamily 2 group A member 1; Transcription factor 14; TCF-14; Transcription factor HNF-4Homo sapiens (human)
C-X-C chemokine receptor type 4CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; Lipopolysaccharide-associated protein 3; LAP-3; LPS-associated protein 3; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptorHomo sapiens (human)
Egl nine homolog 1EC 1.14.11.29; Hypoxia-inducible factor prolyl hydroxylase 2; HIF-PH2; HIF-prolyl hydroxylase 2; HPH-2; Prolyl hydroxylase domain-containing protein 2; PHD2; SM-20Homo sapiens (human)
ATP-dependent 6-phosphofructokinase, liver typeATP-PFK; PFK-L; EC 2.7.1.11; 6-phosphofructokinase type B; Phosphofructo-1-kinase isozyme B; PFK-B; PhosphohexokinaseHomo sapiens (human)
ErythropoietinHomo sapiens (human)
Plasminogen activator inhibitor 1PAI; PAI-1; Endothelial plasminogen activator inhibitor; Serpin E1Homo sapiens (human)
Vascular endothelial growth factor AVEGF-A; Vascular permeability factor; VPFHomo sapiens (human)
Cyclic AMP-responsive element-binding protein 1CREB-1; cAMP-responsive element-binding protein 1Homo sapiens (human)
Nuclear receptor coactivator 1NCoA-1; EC 2.3.1.48; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1Homo sapiens (human)
Solute carrier family 2, facilitated glucose transporter member 3Glucose transporter type 3, brain; GLUT-3Homo sapiens (human)
Alpha-enolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding proteinHomo sapiens (human)
Endothelial transcription factor GATA-2GATA-binding protein 2Homo sapiens (human)
Nuclear receptor coactivator 2NCoA-2; Class E basic helix-loop-helix protein 75; bHLHe75; Transcriptional intermediary factor 2; hTIF2Homo sapiens (human)
NucleophosminNPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; NumatrinHomo sapiens (human)
Hexokinase-1EC 2.7.1.1; Brain form hexokinase; Hexokinase type I; HK I; Hexokinase-AHomo sapiens (human)
5'-nucleotidase5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidaseHomo sapiens (human)
Aryl hydrocarbon receptor nuclear translocatorARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-betaHomo sapiens (human)
Pro-adrenomedullinHomo sapiens (human)
Hexokinase-2EC 2.7.1.1; Hexokinase type II; HK II; Hexokinase-B; Muscle form hexokinaseHomo sapiens (human)
Mothers against decapentaplegic homolog 3MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3Homo sapiens (human)
Transcription factor Sp1Homo sapiens (human)
Stromal cell-derived factor 1SDF-1; hSDF-1; C-X-C motif chemokine 12; Intercrine reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor; PBSFHomo sapiens (human)
Insulin-like growth factor-binding protein 1IBP-1; IGF-binding protein 1; IGFBP-1; Placental protein 12; PP12Homo sapiens (human)
Transferrin receptor protein 1TR; TfR; TfR1; Trfr; T9; p90Homo sapiens (human)
Mothers against decapentaplegic homolog 4MAD homolog 4; Mothers against DPP homolog 4; Deletion target in pancreatic carcinoma 4; SMAD family member 4; SMAD 4; Smad4; hSMAD4Homo sapiens (human)
Proto-oncogene c-FosCellular oncogene fos; G0/G1 switch regulatory protein 7Homo sapiens (human)
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 36PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2Homo sapiens (human)
Prolyl hydroxylase EGLN3EC 1.14.11.-; Egl nine homolog 3; 1.14.11.29; HPH-1; Hypoxia-inducible factor prolyl hydroxylase 3; HIF-PH3; HIF-prolyl hydroxylase 3; HPH-3; Prolyl hydroxylase domain-containing protein 3; PHD3Homo sapiens (human)
Protein NDRG1Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42Homo sapiens (human)
Trefoil factor 3Intestinal trefoil factor; hITF; Polypeptide P1.B; hP1.BHomo sapiens (human)
Class E basic helix-loop-helix protein 40bHLHe40; Class B basic helix-loop-helix protein 2; bHLHb2; Differentially expressed in chondrocytes protein 1; DEC1; Enhancer-of-split and hairy-related protein 2; SHARP-2; Stimulated by retinoic acid gene 13 proteinHomo sapiens (human)
CeruloplasminEC 1.16.3.1; FerroxidaseHomo sapiens (human)
EndoglinHomo sapiens (human)
LeptinObese protein; Obesity factorHomo sapiens (human)
Perilipin-2Adipophilin; Adipose differentiation-related protein; ADRPHomo sapiens (human)
Class E basic helix-loop-helix protein 41bHLHe41; Class B basic helix-loop-helix protein 3; bHLHb3; Differentially expressed in chondrocytes protein 2; hDEC2; Enhancer-of-split and hairy-related protein 1; SHARP-1Homo sapiens (human)
Phosphoglucomutase-1PGM 1; EC 5.4.2.2; Glucose phosphomutase 1Homo sapiens (human)
Protein C-ets-1p54Homo sapiens (human)
DNA-binding protein inhibitor ID-2Class B basic helix-loop-helix protein 26; bHLHb26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2Homo sapiens (human)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3Homo sapiens (human)
Cbp/p300-interacting transactivator 2MSG-related protein 1; MRG-1; P35srjHomo sapiens (human)

Compounds (0)

CompoundDescription