xylose and methotrexate
xylose has been researched along with methotrexate in 8 studies
Compound Research Comparison
| Studies (xylose) | Trials (xylose) | Recent Studies (post-2010) (xylose) | Studies (methotrexate) | Trials (methotrexate) | Recent Studies (post-2010) (methotrexate) |
|---|---|---|---|---|---|
| 7,016 | 78 | 2,365 | 41,593 | 5,666 | 11,969 |
Protein Interaction Comparison
| Protein | Taxonomy | xylose (IC50) | methotrexate (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 1.8 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 0.211 | |
| Toll-like receptor 4 | Homo sapiens (human) | 1.04 | |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 0.08 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0522 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0331 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0348 | |
| Dihydrofolate reductase | Gallus gallus (chicken) | 0.0545 | |
| Dihydrofolate reductase | Enterococcus faecium | 0.0014 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.0138 | |
| Thymidylate synthase | Homo sapiens (human) | 0.343 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0147 | |
| Thymidylate synthase | Escherichia coli K-12 | 0.0181 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1529 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.084 | |
| Folate receptor beta | Homo sapiens (human) | 0.1585 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0011 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.0012 | |
| Folate receptor alpha | Homo sapiens (human) | 0.2263 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0717 | |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | 0.0014 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.01 | |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | 0.01 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Reduced folate transporter | Homo sapiens (human) | 0.012 | |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | 0.0174 | |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | 3.2 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.0547 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.11 | |
| Dihydrofolate reductase | Bacillus anthracis | 0.0136 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0047 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.1207 |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Craft, AW; Kay, H; Lawson, DN; McElwain, TJ | 1 |
| Hepner, GW | 1 |
| Bridges, JM; Glasgow, JF; Pinkerton, CR; Welshman, SG | 1 |
| Cooke, N; Pachman, LM | 1 |
| Gudmand-Høyer, E; Hendel, J; Hendel, L; Johnsen, A | 1 |
| Phelan, MJ; Taylor, W; Thompson, RN; van Heyningen, C; Williams, E | 1 |
| BADENOCH, J; CALLENDER, ST; RYAN, TJ; SALEM, SN; VICKERS, HR | 1 |
| Acar, S; Albayrak, D; Aliyazicioglu, Y; Dagdemir, A; Kanber, Y; Yildirim, H | 1 |
Trials
1 trial(s) available for xylose and methotrexate
| Article | Year |
|---|---|
Does vitamin A prevent high-dose-methotrexate-induced D-xylose malabsorption in children with cancer?
Topics: Adolescent; Antimetabolites, Antineoplastic; Child; Child, Preschool; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Lymphoma, Non-Hodgkin; Malabsorption Syndromes; Male; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prospective Studies; Protective Agents; Retinol-Binding Proteins; Vitamin A; Xylose | 2004 |
Other Studies
7 other study(ies) available for xylose and methotrexate
| Article | Year |
|---|---|
Methotrexate-induced malabsorption in children with acute lymphoblastic leukaemia.
Topics: Child; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Malabsorption Syndromes; Male; Methotrexate; Time Factors; Xylose | 1977 |
The absorption of pteroylglutamic (folic) acid in rats.
Topics: Animals; Folic Acid; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Methotrexate; Phenytoin; Rats; Tritium; Xylose | 1969 |
Enterotoxic effect of methotrexate: does it influence the drug's absorption in children with acute lymphoblastic leukaemia?
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Humans; Intestinal Absorption; Leukemia, Lymphoid; Methotrexate; Xylose | 1981 |
Juvenile dermatomyositis: a clinical and immunologic study.
Topics: Adolescent; Antibodies, Antinuclear; Child; Child, Preschool; Complement System Proteins; Dermatomyositis; Electrocardiography; Esophagus; Female; Gastrointestinal Motility; HLA Antigens; Humans; Immunoglobulins; Infant; Intestinal Absorption; Male; Methotrexate; Prednisone; Respiratory Function Tests; Xylose | 1980 |
Intestinal function and methotrexate absorption in psoriatic patients.
Topics: Adult; Aged; Female; Humans; Intestinal Absorption; Intestines; Male; Methotrexate; Middle Aged; Psoriasis; Xylose | 1982 |
Intestinal absorption in patients with rheumatoid arthritis treated with methotrexate.
Topics: Aged; Arthritis, Rheumatoid; Biopsy; Duodenum; Female; Humans; Intestinal Absorption; Male; Methotrexate; Middle Aged; Xylose | 1993 |
THE TREATMENT OF PSORIASIS WITH FOLIC ACID ANTAGONISTS.
Topics: Aminopterin; Blood Cell Count; Bone Marrow Examination; Drug Therapy; Folic Acid Antagonists; Hemoglobinometry; Humans; Intestinal Absorption; Liver Function Tests; Methotrexate; Psoriasis; Toxicology; Xylose | 1964 |