Page last updated: 2024-12-08
n-acetylthreonine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
N-acetyl-L-threonine : A N-acetyl-L-amino acid that is the N-acetyl derivative of L-threonine. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 152204 |
| CHEBI ID | 45826 |
| SCHEMBL ID | 232441 |
| MeSH ID | M0174724 |
Synonyms (28)
| Synonym |
|---|
| n-acetylthreonine , |
| (2s,3r)-2-acetamido-3-hydroxybutanoic acid |
| AKOS006345008 |
| acetyl-l-threonine |
| 17093-74-2 |
| unii-v0e98v3r9o |
| l-threonine, n-acetyl- |
| v0e98v3r9o , |
| n-acetyl-l-threonine |
| threonine, n-acetyl-, l- |
| s-(+)-n-acetylthreonine |
| SCHEMBL232441 |
| ac-thr-oh |
| AM82242 |
| CHEBI:45826 |
| (2s,3r)-2-acetamido-3-hydroxy-butyric acid |
| DTXSID80168975 |
| mfcd00037810 |
| ac-thr-oh, aldrichcpr |
| J-010668 |
| ammonium n-acetyl-l-threoninate |
| methylammonium n-acetyl-l-threoninate |
| n-methylcarbonylthreonine |
| Q27104560 |
| n-acetyl-threonine; lc-tdda; ce10 |
| (2s,3r)-2-acetamido-3-hydroxybutanoicacid |
| EN300-2991228 |
| CS-0448461 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " No mortalities or evidence of adverse effects were observed in Sprague-Dawley (SD) rats following acute oral administration of 2000 mg of NAT/kg of body weight (kg of bw)." | ( Safety assessment of N-acetyl-L-threonine. Barnett, JF; Delaney, BF; Krsmanovic, L; Myhre, A; Shen, ZA; van de Mortel, EL, 2010) | 0.36 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (2)
| Class | Description |
|---|---|
| N-acetyl-L-amino acid | An L-amino acid having an N-acetyl substituent. |
| L-threonine derivative | A proteinogenic amino acid derivative resulting from reaction of L-threonine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-threonine by a heteroatom. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 17.78
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (17.78) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||