LG 30435: derivative of mequitazine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 72028 |
| CHEMBL ID | 3989846 |
| SCHEMBL ID | 995670 |
| MeSH ID | M0142939 |
| Synonym |
|---|
| lg-30435 |
| mequitamium iodide |
| mequitazium iodide |
| 101396-42-3 |
| 50d69zkz7m , |
| mequitamii iodidum [inn-latin] |
| unii-50d69zkz7m |
| ioduro de mequitamio [inn-spanish] |
| iodure de mequitamium |
| 1-azoniabicyclo(2.2.2)octane, 1-methyl-3-(10h-phenothiazin-10-ylmethyl)-, iodide |
| ioduro de mequitamio |
| iodure de mequitamium [inn-french] |
| mequitamium iodide [inn] |
| 3-(10-h-phenothiazinylmethyl)-1-methyl-1-azabicyclo(2.2.2)octane |
| lg 30435 |
| (+-)-1-methyl-3-(phenothiazin-10-ylmethyl)quinuclidinium iodide |
| mequitamii iodidum |
| mequitaminum iodide |
| (+/-)-1-methyl-3-(phenothiazin-10-ylmethyl)quinuclidinium iodide |
| SCHEMBL995670 |
| 1-azoniabicyclo[2.2.2]octane, 1-methyl-3-(10h-phenothiazin-10-ylmethyl)-, iodide (1:1);1-azoniabicyclo[2.2.2]octane, 1-methyl-3-(10h-phenothiazin-10-ylmethyl)-, iodide (1:1) |
| CHEMBL3989846 |
| Q27260788 |
| 1-methyl-3-[(10h-phenothiazin-10-yl)methyl]-1-azabicyclo[2.2.2]octan-1-ium iodide |
| DTXSID50906129 |
| 10-[(1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl)methyl]phenothiazine;iodide |
| AKOS040748901 |
| mequitazium |
LG 30435 is a new quarternary phenothiazine derivative with H1-antihistaminic and antimuscarinic properties. It is endowed with bronchodilator and antiallergic activity.
| Excerpt | Reference | Relevance |
|---|---|---|
| "LG 30435 is a new quarternary phenothiazine derivative with H1-antihistaminic and antimuscarinic properties. " | ( LG 30435, a new potential antiasthmatic agent. Berti, F; Daffonchio, L; Magni, F; Omini, C; Rossoni, G; Subissi, A, 1989) | 3.16 |
| "LG 30435 is a quaternary phenothiazinic antihistamine, endowed with bronchodilator and antiallergic activity. " | ( LG 30435, a new bronchodilator/antiallergic agent, inhibits PAF-acether induced platelet aggregation and bronchoconstriction. Criscuoli, M; Daffonchio, L; Omini, C; Subissi, A, 1986) | 3.16 |
| "LG 30435 is a new potential anti-asthmatic agent with multiple sites of action. " | ( Effects of LG 30435 on different platelet activating factor-induced responses. Criscuoli, M; Subissi, A, 1988) | 2.11 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " It was poorly absorbed both by the oral and the aerosol routes and it did not appear to penetrate the blood-brain barrier." | ( LG 30435 is a new bronchodilator agent with multiple sites of action. Criscuoli, M; Renzetti, AR; Subissi, A, 1986) | 1.71 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.11) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||