Compounds > cylindrocyclophane a
Page last updated: 2024-11-12

cylindrocyclophane a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

cylindrocyclophane A: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10348304
CHEMBL ID1224866
SCHEMBL ID16431175
MeSH IDM0397447

Synonyms (5)

Synonym
CHEMBL1224866
cylindrocyclophane a
SCHEMBL16431175
(2r,3s,8s,13r,14s,19s)-8,19-dibutyl-3,14-dimethyltricyclo[18.2.2.29,12]hexacosa-1(22),9,11,20,23,25-hexaene-2,10,13,21,24,26-hexol
DTXSID301335544
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (8)

Assay IDTitleYearJournalArticle
AID1289281Antibacterial activity against Klebsiella pneumoniae isolate 18 B224106 after 24 hrs2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
AID1289279Antibacterial activity against Streptococcus pneumoniae ATCC 49619 after 24 hrs2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
AID1289278Antibacterial activity against methicillin-resistant Staphylococcus aureus isolate 1 B690208 after 24 hrs2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
AID1289283Cytotoxicity against human HaCaT cells by Cell titre-blue assay2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
AID504304Cytotoxicity against human HT-29 cells2010Journal of natural products, Sep-24, Volume: 73, Issue:9
Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.
AID1289280Antibacterial activity against Escherichia coli isolate 13 V676803 after 24 hrs2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
AID504303Inhibition of 20S proteasome2010Journal of natural products, Sep-24, Volume: 73, Issue:9
Cylindrocyclophanes with proteasome inhibitory activity from the Cyanobacterium Nostoc sp.
AID1289282Antibacterial activity against Pseudomonas aeruginosa isolate 22 V143708 after 24 hrs2016Journal of natural products, Jan-22, Volume: 79, Issue:1
Cylindrofridins A-C, Linear Cylindrocyclophane-Related Alkylresorcinols from the Cyanobacterium Cylindrospermum stagnale.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.30 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
mitoxantrone
Mitoxantrone: An anthracenedione-derived antineoplastic agent.. mitoxantrone : A dihydroxyanthraquinone that is 1,4-dihydroxy-9,10-anthraquinone which is substituted by 6-hydroxy-1,4-diazahexyl groups at positions 5 and 8.		2.1310dihydroxyanthraquinoneanalgesic;
antineoplastic agent
camptothecin
NSC 100880: carboxylate (opened lactone) form of camptothecin; RN refers to (S)-isomer; structure given in first source		2.0510delta-lactone;
pyranoindolizinoquinoline;
quinoline alkaloid;
tertiary alcohol		antineoplastic agent;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
genotoxin;
plant metabolite
alkenes
[no description available]		210
bortezomib
[no description available]		2.0510amino acid amide;
L-phenylalanine derivative;
pyrazines		antineoplastic agent;
antiprotozoal drug;
protease inhibitor;
proteasome inhibitor
fusidic acid
Fusidic Acid: An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed). It acts by inhibiting translocation during protein synthesis.. fusidic acid : A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.		2.131011alpha-hydroxy steroid;
3alpha-hydroxy steroid;
alpha,beta-unsaturated monocarboxylic acid;
steroid acid;
steroid antibiotic;
sterol ester		EC 2.7.1.33 (pantothenate kinase) inhibitor;
Escherichia coli metabolite;
protein synthesis inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials