Assay ID | Title | Year | Journal | Article |
AID403240 | Cytotoxicity against human SKOV3 cells | 1997 | Journal of natural products, Mar, Volume: 60, Issue:3
| Three new cryptophycins from Nostoc sp. GSV 224. |
AID214529 | In vitro effective concentration required to reduce the amount of microtubules assembly by tubulin assay | 2004 | Journal of medicinal chemistry, Jan-29, Volume: 47, Issue:3
| Total synthesis and antitubulin activity of c10 analogues of cryptophycin-24. |
AID403242 | Cytotoxicity against human KB cells | 1997 | Journal of natural products, Mar, Volume: 60, Issue:3
| Three new cryptophycins from Nostoc sp. GSV 224. |
AID103090 | In vitro cytotoxicity against human MCF-7/Adr breast cancer cell line | 2004 | Journal of medicinal chemistry, Jan-29, Volume: 47, Issue:3
| Total synthesis and antitubulin activity of c10 analogues of cryptophycin-24. |
AID403241 | Cytotoxicity against human LoVo cells | 1997 | Journal of natural products, Mar, Volume: 60, Issue:3
| Three new cryptophycins from Nostoc sp. GSV 224. |
AID235113 | Resistance factor was expressed as the IC50 of resistance cell line / IC50 of sensitive cell line | 2004 | Journal of medicinal chemistry, Jul-01, Volume: 47, Issue:14
| Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24. |
AID103723 | In vitro cytotoxicity against human MCF-7 cell line | 2004 | Journal of medicinal chemistry, Jan-29, Volume: 47, Issue:3
| Total synthesis and antitubulin activity of c10 analogues of cryptophycin-24. |
AID103750 | Inhibitory activity against MCF-7 cells after 72 hr cell growth | 2003 | Bioorganic & medicinal chemistry letters, Feb-24, Volume: 13, Issue:4
| Cryptophycin affinity labels: synthesis and biological activity of a benzophenone analogue of cryptophycin-24. |
AID88942 | Antiproliferative activity was evaluated by the 72 hr MTT cell viability assay using human colon carcinoma cells (GC3). | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Synthesis and biological evaluation of novel cryptophycin analogs with modification in the beta-alanine region. |
AID104087 | In vitro inhibitory activity of compound against induced cytotoxicity in MCF-7 cell line | 2004 | Journal of medicinal chemistry, Jul-01, Volume: 47, Issue:14
| Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24. |
AID224783 | Compound was tested for its antitumor activity in murine pancreatic adenocarcinoma PO3 model at the maximum tolerated dose(MTD) | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Synthesis and biological evaluation of novel cryptophycin analogs with modification in the beta-alanine region. |
AID333122 | Cytotoxicity against human KB cells | 2004 | Journal of natural products, Aug, Volume: 67, Issue:8
| Isolation and structure determination of cryptophycins 38, 326, and 327 from the terrestrial cyanobacterium Nostoc sp. GSV 224. |
AID126108 | Tested in vitro for the concentration that reduces the amount of pelleted protein by 50% in microtubule assembly assay. | 1998 | Bioorganic & medicinal chemistry letters, Aug-04, Volume: 8, Issue:15
| Halohydrin analogues of cryptophycin 1: synthesis and biological activity. |
AID103086 | In vitro inhibitory activity of compound against induced cytotoxicity in multidrug-resistant MCF-7/ADR breast cancer cell line | 2004 | Journal of medicinal chemistry, Jul-01, Volume: 47, Issue:14
| Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24. |
AID103764 | Inhibitory activity against MCF7-ADR cells after 72 hr cell growth | 2003 | Bioorganic & medicinal chemistry letters, Feb-24, Volume: 13, Issue:4
| Cryptophycin affinity labels: synthesis and biological activity of a benzophenone analogue of cryptophycin-24. |
AID226696 | In vitro inhibitory activity of compound against microtubule polymerization in a tubulin assembly assay | 2004 | Journal of medicinal chemistry, Jul-01, Volume: 47, Issue:14
| Total synthesis and anti-tubulin activity of epi-c3 analogues of cryptophycin-24. |
AID80697 | Inhibitory activity against HCT116 cells after 24 hr cell growth | 2003 | Bioorganic & medicinal chemistry letters, Feb-24, Volume: 13, Issue:4
| Cryptophycin affinity labels: synthesis and biological activity of a benzophenone analogue of cryptophycin-24. |
AID214507 | Concentration required to reduce the amount of pelleted tubulin | 2003 | Bioorganic & medicinal chemistry letters, Feb-24, Volume: 13, Issue:4
| Cryptophycin affinity labels: synthesis and biological activity of a benzophenone analogue of cryptophycin-24. |
AID38061 | Tested in vitro for the concentration that inhibits the proliferation of B16 melanoma cells by 50% after 72 hr of growth in cell proliferation assay | 1998 | Bioorganic & medicinal chemistry letters, Aug-04, Volume: 8, Issue:15
| Halohydrin analogues of cryptophycin 1: synthesis and biological activity. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |