Assay ID | Title | Year | Journal | Article |
AID44346 | In vitro growth inhibitory activity in the human CCRF-CEM leukemia cell line. | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID120737 | Ratio of the median tumor weight in the treatment group over the median tumor weight in the control group on a schedule of 3-10 days and at a total dose of 32 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID88942 | Antiproliferative activity was evaluated by the 72 hr MTT cell viability assay using human colon carcinoma cells (GC3). | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Synthesis and biological evaluation of novel cryptophycin analogs with modification in the beta-alanine region. |
AID111305 | In vivo antitumor activity against murine pancreatic adenocarcinoma and measured as number of deaths on a schedule of 3-9 days and at a total dose of 42 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID1918879 | Cytotoxicity against human KB 3-1 cells assessed as reduction in cell viability | 2022 | Journal of natural products, 12-23, Volume: 85, Issue:12
| Bioactive Arylnaphthalide Lignans from |
AID111304 | In vivo antitumor activity against murine pancreatic adenocarcinoma and measured as number of deaths on a schedule of 3-10 days and at a total dose of 32 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID726203 | Cytotoxicity against human KB-3-1 cells by resazurin reduction assay | 2013 | Journal of medicinal chemistry, Mar-14, Volume: 56, Issue:5
| Conjugates of modified cryptophycins and RGD-peptides enter target cells by endocytosis. |
AID124782 | In vivo antitumor activity against murine pancreatic adenocarcinoma and measured as % weight loss on a schedule of 3-9 days and at a total dose of 42 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID224783 | Compound was tested for its antitumor activity in murine pancreatic adenocarcinoma PO3 model at the maximum tolerated dose(MTD) | 1999 | Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
| Synthesis and biological evaluation of novel cryptophycin analogs with modification in the beta-alanine region. |
AID120738 | Ratio of the median tumor weight in the treatment group over the median tumor weight in the control group on a schedule of 3-9 days and at a total dose of 42 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID124781 | In vivo antitumor activity against murine pancreatic adenocarcinoma and measured as % weight loss on a schedule of 3-10 days and at a total dose of 32 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
AID726202 | Cytotoxicity against human KBV1 cells by resazurin reduction assay | 2013 | Journal of medicinal chemistry, Mar-14, Volume: 56, Issue:5
| Conjugates of modified cryptophycins and RGD-peptides enter target cells by endocytosis. |
AID43714 | In vitro cytotoxicity against human leukemia CCRF-CEM cell line | 1999 | Bioorganic & medicinal chemistry letters, Feb-08, Volume: 9, Issue:3
| Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region). |
AID115257 | Log cell kill of tumor bearing mice on a schedule of 3-10 days and at a total dose of 32 mg/kg | 2003 | Journal of medicinal chemistry, Jul-03, Volume: 46, Issue:14
| A convergent approach to cryptophycin 52 analogues: synthesis and biological evaluation of a novel series of fragment a epoxides and chlorohydrins. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |