Compounds > coroxon
Page last updated: 2024-12-05

coroxon

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

coroxon: oxygen analog of coumaphos [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9453
CHEMBL ID1891727
SCHEMBL ID669657
MeSH IDM0050119

Synonyms (37)

Synonym
einecs 206-288-6
phosphoric acid, diethyl ester, ester with 3-chloro-7-hydroxy-4-methylcoumarin
o,o-di(2-chloroethyl)-7-(3-chloro-4-methylcoumarinyl)phosphate
coroxon
o,o-diethyl o-(3-chloro-4-methylcoumarin-7-yl) phosphate
brn 1266025
diethyl 3-chloro-4-methyl-7-coumarinyl phosphate
3-chloro-4-methyl-2-oxo-2h-1-benzopyran-7-yl diethyl phosphate
3-chloro-4-methyl-7-coumarinyl diethyl phosphate
coumarin, 3-chloro-7-hydroxy-4-methyl-, diethyl phosphate
NCGC00163950-01
(3-chloro-4-methyl-2-oxochromen-7-yl) diethyl phosphate
321-54-0
coralox
NCGC00163950-02
unii-fs49k9q80b
phosphoric acid, 3-chloro-4-methyl-2-oxo-2h-1-benzopyran-7-yl diethyl ester
fs49k9q80b ,
coumaphos-oxon
AKOS015965590
coumaphos oxon
o,o-diethyl o-(3-chloro-4-methyl-7-coumarinyl) phosphate
3-chloro-4-methylumbelliferone diethyl phosphate
coroxon [mi]
o,o-diethyl o-7-(3-chloro-4-methylumbelliferone) phosphate
3-chloro-7-hydroxy-4-methylcoumarin diethyl phosphate
phosphoric acid 3-chloro-4-methyl-2-oxo-2h-1-benzopyran-7-yl diethyl ester
SCHEMBL669657
CHEMBL1891727
FDYMERLIFOUIRZ-UHFFFAOYSA-N
3-chloro-4-methyl-2-oxo-2h-chromen-7-yl diethyl phosphate #
DTXSID1037513
AS-67630
J-018656
phosphoric acid 3-chloro-4-methyl-2-oxo-2h-chromen-7-yl ester diethyl ester
3-chloro-4-methyl-2-oxo-2h-chromen-7-yl diethyl phosphate
Q27278165
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
pregnane X nuclear receptorHomo sapiens (human)Potency44.66840.005428.02631,258.9301AID720659
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency17.03900.001019.414170.9645AID588536; AID588537
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency44.66840.010039.53711,122.0200AID588545
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.64

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.64 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.64)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chlorpyrifos
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.		1.9710chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
coumaphos
Coumaphos: A organothiophosphorus cholinesterase inhibitor that is used as an anthelmintic, insecticide, and as a nematocide.		3.0850organic thiophosphate;
organochlorine compound;
organothiophosphate insecticide		acaricide;
agrochemical;
antinematodal drug;
avicide;
EC 3.1.1.8 (cholinesterase) inhibitor
paraoxon
[no description available]		1.9710aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
diazoxon
diazoxon: a pesticide; structure. diazoxon : An organic phosphate that is diethyl hydrogen phosphate in which the hydrogen of the hydroxy group has been replaced by a 6-methyl-2-(propan-2-yl)pyrimidin-4-yl group. It is a metabolite of the pesticide diazinon.		1.9710organic phosphate;
pyrimidines		marine xenobiotic metabolite
o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate
[no description available]		1.9710
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.		1.9510benzenes;
hydroxycoumarin;
methyl ketone
ConditionIndicatedRelationship StrengthStudiesTrials