carpaine: papaya alkaloid; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
carpaine : An alkaloid that forms a major component of the papaya leaves and has been shown to exhibit cardiovascular effects. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Papaya | genus | [no description available] | Caricaceae | A plant family of the order Violales, subclass Dilleniidae, class Magnoliopsida.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 442630 |
| CHEBI ID | 3433 |
| SCHEMBL ID | 1443089 |
| MeSH ID | M0070053 |
| Synonym |
|---|
| 3463-92-1 |
| C10135 , |
| carpaine |
| SCHEMBL1443089 |
| einecs 222-414-2 |
| 13,26-dimethyl-2,15-dioxa-12,25-diazatricyclotriacontane-3,16-dione |
| vlr223h4qp , |
| unii-vlr223h4qp |
| (+)-carpaine |
| carpaine [mi] |
| 2,15-dioxa-12,25-diazatricyclo(22.2.2.211,14)triacontane-3,16-dione, 13,26-dimethyl-, (1s,11r,13s,14s,24r,26s)- |
| carpaine, (+)- |
| (1s-(1r*,11s*,13r*,14r*,24s*,26r*))-13,26-dimethyl-2,15-dioxa-12,25-diazatricyclo(22.2.2.211,14)triacontane-3,16-dione |
| CHEBI:3433 , |
| (1s,11r,13s,14s,24r,26s)-13,26-dimethyl-2,15-dioxa-12,25-diazatricyclo[22.2.2.211,14]triacontane-3,16-dione |
| AC-34190 |
| Q3179543 |
| CS-0101579 |
| HY-N7016 |
| DTXSID801026582 |
| PD143305 |
| (1s,11r,13s,14s,24r,26s)-13,26-dimethyl-2,15-dioxa-12,25-diazatricyclo(22.2.2.211,14)triacontane-3,16-dione |
| AKOS040732717 |
| Role | Description |
|---|---|
| plant metabolite | Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. |
| cardiovascular drug | A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| alkaloid | Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. |
| macrodiolide | A macropolylide which contains two ester linkages in one macrocyclic ring. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (56.20) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (14.29%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (85.71%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||