Page last updated: 2024-12-06

cannabicyclol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cannabicyclol (CBC) is a minor cannabinoid found in the cannabis plant. It is a structural isomer of cannabichromene (CBC), meaning it has the same chemical formula but a different arrangement of atoms. CBC is formed through the decarboxylation of cannabichromene acid (CBCA). While research on CBC is still ongoing, preliminary studies suggest it may possess potential therapeutic benefits. CBC is believed to exhibit anti-inflammatory, analgesic, and neuroprotective properties. Its effects are thought to be mediated through interaction with the endocannabinoid system, particularly the CB2 receptor. The study of CBC is driven by its potential as a therapeutic agent for conditions such as pain, inflammation, and neurological disorders. Further research is needed to understand its full pharmacological profile and therapeutic applications.'

Cross-References

ID SourceID
PubMed CID30607
CHEMBL ID154127
SCHEMBL ID455022
MeSH IDM0077972

Synonyms (17)

Synonym
pentylcannabicyclol
cannabipinol
cannabicyclol
1h-4-oxabenzo(f)cyclobut(cd)inden-8-ol, 1a-alpha,2,3,3a,8b-alpha,8c-alpha-hexahydro-1,1,3a-trimethyl-6-pentyl-
(1ar-(1aalpha,3aalpha,8balpha,8calpha))-1a,2,3,3a,8b,8c-hexahydro-1,1,3a-trimethyl-6-pentyl-1h-4-oxabenzo(f)cyclobut(cd)inden-8-ol
CHEMBL154127
21366-63-2
unii-mp5wzk8m5u
SCHEMBL455022
IGHTZQUIFGUJTG-UHFFFAOYSA-N
1,1,3a-trimethyl-6-pentyl-1a,2,3,3a,8b,8c-hexahydro-1h-4-oxabenzo[f]cyclobuta[cd]inden-8-ol #
1h-4-oxabenzo[f]cyclobut[cd]inden-8-ol, 1a,2,3,3a,8b,8c-hexahydro-1,1,3a-trimethyl-6-pentyl-, [1ar-(1a.alpha.,3a.alpha.,8b.alpha.,8c.alpha.)]-
1h-4-oxabenzo(f)cyclobut(cd)inden-8-ol, 1a-.alpha.,2,3,3a,8b-.alpha.,8c-.alpha.-hexahydro-1,1,3a-trimethyl-6-pentyl-
DTXSID70900962
Q907909
9,13,13-trimethyl-5-pentyl-8-oxatetracyclo[7.4.1.02,7.012,14]tetradeca-2,4,6-trien-3-ol
BC175207
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID165405Capability to induce convulsions in tetrahydrocannabinol-seizure susceptible (THC-SS) rabbit1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Use of a potential rabbit model for structure--behavioral activity studies of cannabinoids.
AID167514Number of rabbits convulsed at 20 mg/kg, iv out of 2 rabbits tested1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Use of a potential rabbit model for structure--behavioral activity studies of cannabinoids.
AID167522Number of rabbits convulsed at 8 mg/kg, iv out of 1 rabbit tested1982Journal of medicinal chemistry, May, Volume: 25, Issue:5
Use of a potential rabbit model for structure--behavioral activity studies of cannabinoids.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's3 (37.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.96 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index36.71 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]